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Current Advances in Structural Heart Interventions
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Current Advances in Structural Heart Interventions

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 7 July 2024 | Viewed by 1400

Special Issue Editors

Dr. Stéphane Noble

E-Mail Website
Guest Editor
Division of Cardiology, Department of Medicine, Geneva University Hospitals, 1205 Geneva, Switzerland
Interests: cardiology; cardiovascular system; interventional cardiology; structural heart intervention; echocardiography; aortic valve; transcatheter edge-to-edge valve repair; tricuspid valve; mitral valve; left atrial appendage closure; patent foramen ovale closure
Dr. Hajo Müller

E-Mail Website
Guest Editor
Division of Cardiology, Department of Medicine, Geneva University Hospitals, 1205 Geneva, Switzerland
Interests: cardiology; cardiovascular system; echocardiography; transthoracic echocardiography; transoesophageal echocardiography; intra-cardiac echocardiography; structural heart intervention guidance; aortic valve; transcatheter edge-to-edge valve repair; tricuspid valve; mitral valve; left atrial appendage closure; patent foramen ovale closure

Special Issue Information

Dear Colleagues,

Structural heart interventions are an expanding subspecialty of interventional cardiology that include any transcatheter noncoronary cardiovascular interventions. Imaging, mainly echocardiography and CT scans, are essential in this field. During the last two decades, the transcatheter approach for valvulopathy treatment has been developing at a fast pace, with options now available for all four valves. Randomized data show the benefit of patent foramen ovale closure in the context of a paradoxical stroke, but there are still unanswered questions. Similarly, growing experience and data on left appendage closure also show the benefit of left appendage closure, but continuous efforts are needed to reduce the unresolved issues.

The scope of this Special Issue is to provide an overview of the latest data in structural heart interventions. Preprocedural planning and assessment, imaging guidance during the procedure, and postprocedural management are of great interest in order to improve the outcomes of and provide the best lifetime management for these patients.

We encourage authors to submit an original article or a state-of-the art review to this Special Issue.

Dr. Stéphane Noble
Dr. Hajo Müller
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • transcatheter edge-to-edge repair
  • transcatheter aortic valve implantation
  • valvulopathy
  • cardiac imaging
  • CT scan
  • echocardiography
  • patent foramen ovale
  • left atrial appendage closure

Published Papers (1 paper)

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Research

15 pages, 3288 KiB  
Article
Incidence and Outcomes of Valve-in-Valve Transcatheter Aortic Valve Implantation in Failed Bioprosthetic Valves
by Thorald Stolte, Jasper Boeddinghaus, Giampiero Allegra, Gregor Leibundgut, Oliver Reuthebuch, Christoph Kaiser, Christian Müller and Thomas Nestelberger
J. Clin. Med. 2023, 12(18), 5868; https://doi.org/10.3390/jcm12185868 - 9 Sep 2023
Viewed by 1010
Abstract
Introduction: Transcatheter aortic valve replacement (TAVR) has become a widely used, comparably efficient and safe alternative to surgical aortic valve replacement (SAVR). Its utilization continues to grow, especially among younger patients. Despite improvements in durability, degeneration and subsequent re-interventions of failed prosthetic valves [...] Read more.
Introduction: Transcatheter aortic valve replacement (TAVR) has become a widely used, comparably efficient and safe alternative to surgical aortic valve replacement (SAVR). Its utilization continues to grow, especially among younger patients. Despite improvements in durability, degeneration and subsequent re-interventions of failed prosthetic valves are still common. Even though valve-in-valve procedures have become more frequent, little is known about the trends over time or about clinical and echocardiographic long-term outcomes. Materials and Methods: Patients who underwent a valve-in-valve procedure between December 2011 and December 2022 in a large tertiary university hospital were analyzed. Primary outcomes were defined as procedural and device successes as well as event-free survival. Secondary analyses between subsets of patients divided by index valve and date of procedure were performed. Results: Among 1407 procedures, 58 (4%) were valve-in-valve interventions, with an increased frequency observed over time. Overall, technical success was achieved in 88% and device success in 85% of patients. Complications were predominantly minor, with similar success rates among TAVR-in-SAVR (TiSAVR) and TAVR-in-TAVR (TiTAVR). Notably, there were significant and lasting improvements in mean echocardiographic gradients at 1 year. Event-free survival was 76% at one month and 69% at one year. Conclusions: Over the last decade, a rising trend of valve-in-valve procedures was observed. Despite an increase in procedures, complications show a contrasting decline with improved technical and device success over time. TiSAVR and TiTAVR showed comparable rates of procedural and device success as well as similar outcomes, highlighting the utility of valve-in-valve procedures in an aging population. Full article
(This article belongs to the Special Issue Current Advances in Structural Heart Interventions)
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