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Ventilation in Critical Care Medicine
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Ventilation in Critical Care Medicine

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Intensive Care".

Deadline for manuscript submissions: 20 May 2024 | Viewed by 1224

Special Issue Editor

Dr. Gianluca Zani

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Guest Editor
Anesthesia and Intensive Care Unit, Santa Maria delle Croci Hospital, AUSL Romagna, Ravenna, Italy
Interests: ventilation; acute respiratory failure; ICU; anesthesia

Special Issue Information

Dear Colleagues,

Mechanical ventilation is a common and often life-saving intervention in critically ill patients, and it can be carried out in many different ways. For example, the decision to perform invasive or non-invasive ventilation, with which the device and location (ICU, operation theater or NORA), how to set the tidal volume and PEEP, the utility of the prone position and weaning strategies are still debated topics. The avoidance of ventilation-induced lung damage through a protective ventilation approach is currently a major focus of clinical interest. However, despite multiple studies having been produced, the number of issues for which we are in the dark still outnumbers those for which we are certain. The COVID-19 pandemic has highlighted the fragility of us all, emphasizing the role of a suitable ventilation strategy related to perfusion and also the importance of both clinical and physiological studies. Ventilation is moving towards goal-directed therapy, the result of replicable measurements to verify the effectiveness of the treatment and possibly make changes in real time.

This Special Issue aims to provide new information on pathological mechanisms, examination and treatment methods for critically ill patients to personalize ventilation. We invite the submission of original research papers as well as contemporary review articles that reflect the latest progress in and potential of this research field.

Dr. Gianluca Zani
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • invasive ventilation
  • non-invasive ventilation
  • acute respiratory failure
  • best PEEP
  • respiratory weaning
  • respiratory mechanics
  • ventilation and perfusion
  • personalized ventilation

Published Papers (1 paper)

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9 pages, 7878 KiB  
Case Report
Ventilation Management in a Patient with Ventilation–Perfusion Mismatch in the Early Phase of Lung Injury and during the Recovery
by Ana Cicvarić, Josipa Glavaš Tahtler, Tajana Turk, Sanda Škrinjarić-Cincar, Despoina Koulenti, Nenad Nešković, Mia Edl and Slavica Kvolik
J. Clin. Med. 2024, 13(3), 871; https://doi.org/10.3390/jcm13030871 - 2 Feb 2024
Viewed by 967
Abstract
Chest trauma is one of the most serious and difficult injuries, with various complications that can lead to ventilation–perfusion (V/Q) mismatch and systemic hypoxia. We are presenting a case of a 53-year-old male with no chronic therapy who was admitted to the Intensive [...] Read more.
Chest trauma is one of the most serious and difficult injuries, with various complications that can lead to ventilation–perfusion (V/Q) mismatch and systemic hypoxia. We are presenting a case of a 53-year-old male with no chronic therapy who was admitted to the Intensive Care Unit due to severe respiratory failure after chest trauma. He developed a right-sided pneumothorax, and then a thoracic drain was placed. On admission, the patient was hemodynamically unstable and tachypneic. He was intubated and mechanically ventilated, febrile (38.9 °C) and unconscious. A lung CT showed massive non-ventilated areas, predominantly in the right lung, guiding repeated therapeutic and diagnostic bronchoalveolar lavages. He was ventilated with PEEP of 10 cmH2O with a FiO2 of 0.6–0.8. Empirical broad-spectrum antimicrobial therapy was immediately initiated. Both high FiO2 and moderate PEEP were maintained and adjusted according to the current blood gas values and oxygen saturation. He was weaned from mechanical ventilation, and non-invasive oxygenation was continued. After Stenotrophomonas maltophilia was identified and treated with sulfamethoxazole/trimethoprim, a regression of lung infiltrates was observed. In conclusion, both ventilatory and antibiotic therapy were needed to improve the oxygenation and outcome of the patient with S. maltophilia pneumonia and V/Q mismatch. Full article
(This article belongs to the Special Issue Ventilation in Critical Care Medicine)
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