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Recent Progress in Multiple Sclerosis and Migraine
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Recent Progress in Multiple Sclerosis and Migraine

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 381

Special Issue Editors

Dr. Paolo Immovilli

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Guest Editor
The Neurology Unit, Emergency Department, Guglielmo da Saliceto Hospital, Via Taverna 39, 29121 Piacenza, Italy
Interests: multiple sclerosis; stroke; COVID-19; clinical neurology; epilepsy
Dr. Eugenia Rota

E-Mail Website
Guest Editor
Neurology Unit, San Giacomo Hospital, ASL Alessandria, Via E. Raggio 12, 15067 Novi Ligure, Italy
Interests: headache; stroke; epilepsy; neurophysiology

Special Issue Information

Dear Colleagues,

Multiple sclerosis (MS) and migraine are chronic and progressive neurological diseases that affect millions of people worldwide. Despite recent advancements in understanding the disease, there is still a need for continued research to improve diagnosis and treatment options. Diagnosis and assessment of MS and migraine, including imaging techniques, clinical diagnosis, and laboratory tests. We invite experts and professionals from various fields to submit original research articles and review papers related to multiple sclerosis and migraine. The scope of this journal edition will include but is not limited to

  • Diagnosis and assessment of MS and migraine, including cerebrospinal fluid analysis, imaging techniques and clinical diagnosis;
  • Novel and emerging therapies for MS and migraine, such as disease-modifying drugs and symptom management techniques;
  • Multidisciplinary approaches to managing MS and migraine, including rehabilitation, psychological support, and lifestyle interventions.

Dr. Paolo Immovilli
Dr. Eugenia Rota
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • clinical neurology
  • multiple sclerosis
  • migraine
  • brain diseases
  • epilepsy
  • emerging diagnostics
  • MRI

Published Papers (1 paper)

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Research

11 pages, 697 KiB  
Article
Alexithymia Increases Pericranial and Cervical Muscle Tenderness in Women with Migraine
by Eugenia Rota, Elisa Cavagnetto, Paolo Immovilli, Enrico Frola, Pavel Salari, Nicola Morelli and Alessandro Battaggia
J. Clin. Med. 2024, 13(10), 2772; https://doi.org/10.3390/jcm13102772 - 8 May 2024
Viewed by 280
Abstract
Background/Objectives: Alexithymia is characterized by a deficit in identifying and communicating feelings. Emerging evidence suggests that alexithymia is highly prevalent in migraine, in a complex interplay with psychiatric comorbidity. Pericranial/cervical muscle tenderness is a remarkable clinical feature in a large proportion of migraine [...] Read more.
Background/Objectives: Alexithymia is characterized by a deficit in identifying and communicating feelings. Emerging evidence suggests that alexithymia is highly prevalent in migraine, in a complex interplay with psychiatric comorbidity. Pericranial/cervical muscle tenderness is a remarkable clinical feature in a large proportion of migraine patients. This pilot study aimed at investigating the relationship between alexithymia and pericranial/cervical muscle tenderness in female migraineurs. Methods: A total of 42 female patients fulfilling the diagnostic criteria for migraine were enrolled into this pilot, observational, cross-sectional study after informed consent was obtained. Each patient underwent a psychological assessment to identify any alexithymia by means of TAS-20, anxiety/mood comorbidity (by means of STAI-Y1 STAI-Y2, BDI-II), and migraine-related disability (by means of HIT-6), and a physical cranial/cervical musculoskeletal examination. Palpation of pericranial and cervical muscles was carried out in the standardized manner. A Cumulative Muscle Tenderness (CUM) score (0–6) was calculated for each patient. A multivariate analysis was performed to investigate any association amongst the TAS-20 score, the CUM score, and the following covariates: BDI-II, STAI-Y1, STAI-Y2, and HIT-6 scores, age, disease duration, monthly migraine days, and average head pain intensity in the previous three months. Results: Overall, 35.6% of the sample had alexithymia. The multivariate analysis detected a linear and independent relationship between the TAS-20 and CUM scores, with a statistically significant (p = 0.017) association. Conclusions: This pilot study suggests that alexithymia plays a role in increasing pericranial/cervical muscle tenderness in migraine, independently from psychiatric comorbidity. A novel therapeutical approach, targeting alexithymia, may well reduce muscular tenderness in female migraineurs. Full article
(This article belongs to the Special Issue Recent Progress in Multiple Sclerosis and Migraine)
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