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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cancer Genomics submission deadline 20 Sep 2024 | 5 articles | Viewed by 7400 | Submission Open
Keywords: precision oncology; cancer genomics; personalized medicine; mutagenesis; molecular epidemiology
(This special issue belongs to the Section Molecular Oncology)
Molecular Insights into Thrombosis
edited by
submission deadline 20 Sep 2024 | 4 articles | Viewed by 7175 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Advances in Herpesviruses
edited by
submission deadline 20 Sep 2024 | 6 articles | Viewed by 7167 | Submission Open
(This special issue belongs to the Section Molecular Microbiology)
Targeting of Functional Proteins in Disease Therapeutics: Enzyme Function and Inhibition Studies submission deadline 20 Sep 2024 | 4 articles | Viewed by 7166 | Submission Open
Keywords: enzymes; disease therapeutics; inhibitior
(This special issue belongs to the Section Biochemistry)
Cutting Edge Advances in Prostate Cancer submission deadline 20 Sep 2024 | 5 articles | Viewed by 7053 | Submission Open
Keywords: prostate cancer; prognostic and diagnostic biomarkers; therapy resistance; tumor microenvironment; molecular biology
(This special issue belongs to the Section Molecular Oncology)
Gap Junction Channels and Hemichannels in Health and Disease: 2nd Edition submission deadline 20 Sep 2024 | 6 articles | Viewed by 7014 | Submission Open
Keywords: gap junction channel; hemichannel; CaM; calmodulin
(This special issue belongs to the Section Biochemistry)
Techniques and Strategies in Drug Design and Discovery, 2nd Edition submission deadline 20 Sep 2024 | 6 articles | Viewed by 6824 | Submission Open
Keywords: drug discovery; drug development; target identification; computational drug design; structure-based drug design; ligand-based drug design
(This special issue belongs to the Section Molecular Pharmacology)
Recent Molecular Biology on Ovarian Cancer and Prostate Cancer
edited by and Mónica Lamas-Maceiras
submission deadline 20 Sep 2024 | 2 articles | Viewed by 6797 | Submission Open
Keywords: ovarian cancer; prostate cancer; ncRNAs; genetic screening; advanced imaging techniques; biomarkers; immunotherapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mitochondria-Mediated Oxidative Stress in Diseases: Cell Death and Treatment submission deadline 20 Sep 2024 | 5 articles | Viewed by 6476 | Submission Open
Keywords: mitochondrial dysfunction; reactive oxygen species; oxidative stress; mitochondrial biogenesis; mitotherapy; neurodegenerative diseases; cardiovascular diseases; cancer; biomarkers; mitochondrial dynamics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Metabolic Regulation in the Development of Cardiovascular Disease and Heart Failure, 2nd Edition
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 6385 | Submission Open
Keywords: diabetes; metabolism; dyslipidemia; cardiovascular disease; heart failure; diagnosis; prognosis; therapy
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Eosinophilic Esophagitis: Molecular Mechanisms, Diagnosis, and Therapeutic Strategies
edited by Francesca Racca and Gaia Pellegatta
submission deadline 20 Sep 2024 | 3 articles | Viewed by 6383 | Submission Open
Keywords: real-world data; esophageal delivery; non-invasive diagnostic methodologies; molecular mechanisms; therapeutic strategies; comorbidities; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Challenges and Perspectives in Polycystic Ovary Syndrome
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 6271 | Submission Open
Keywords: polycystic ovary syndrome; evolutionary origins; developmental origins; pathogenesis; pathophysiology; microbiome; pregnancy complications; lifestyle
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research on Epigenetic Modifications
edited by , Mariella Cuomo and
submission deadline 20 Sep 2024 | 2 articles | Viewed by 6269 | Submission Open
Keywords: epigenetic modifications; chromatin remodeling; transcription factors; RNA modification; histones; methylation; diseases; epigenetic drugs development
(This special issue belongs to the Section Molecular Genetics and Genomics)
Computational Modelling and Molecular Dynamics Simulations of Biological Systems
edited by
submission deadline 20 Sep 2024 | 5 articles | Viewed by 6191 | Submission Open
Keywords: molecular dynamics simulations; coarse-graining approaches; computational biophysics; agent-based modeling; mechanistic modeling; multiscale modeling; machine learning; protein structure and function
(This special issue belongs to the Section Molecular Informatics)
Design, Synthesis, and Modification of Efficient Catalyst Materials submission deadline 20 Sep 2024 | 5 articles | Viewed by 5862 | Submission Open
Keywords: surface modification; heterogeneous and homogenous catalysis; surface/texture chemistry; physicochemical characterization of catalytic materials; the applications of catalysts; for example; in environmental processes
(This special issue belongs to the Section Materials Science)
Recent Research on Antimicrobial Agents
edited by and
submission deadline 20 Sep 2024 | 4 articles | Viewed by 5840 | Submission Open
Keywords: antimicrobial; antibiotic; multidrug resistant microorganisms; natural products; byproducts; biofilms
(This special issue belongs to the Section Molecular Pharmacology)
Sarcomeric Proteins in Health and Disease: 3rd Edition
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 5521 | Submission Open
(This special issue belongs to the Section Molecular Biophysics)
Novel Pharmacology of Diabetic Complications
edited by and Richard Hulse
submission deadline 20 Sep 2024 | 1 articles | Viewed by 5416 | Submission Open
Keywords: diabetes mellitus; complication; pathophysiology; mechanism; therapeutic strategies
(This special issue belongs to the Section Molecular Pharmacology)
New Diagnostic Tools and Biomarkers in Oncological Diseases: 2nd Edition
edited by
submission deadline 20 Sep 2024 | 4 articles | Viewed by 5354 | Submission Open
Keywords: oncologic diseases; biomarkers; liquid biopsy; miRNA; ncRNA; exosomes
(This special issue belongs to the Section Molecular Oncology)
Novel Therapeutic Strategies for Neurodegenerative Disease submission deadline 20 Sep 2024 | 2 articles | Viewed by 5303 | Submission Open
Keywords: neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease; therapy
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Approaches to Male Infertility: From Diagnosis to Decision-Making submission deadline 20 Sep 2024 | 3 articles | Viewed by 5295 | Submission Open
Keywords: male infertility; sperm; omics; epigenome; transcriptome; proteome; metabolome; assisted reproductive technique (ART)
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
The Role of Glycosaminoglycans in Human Diseases
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 5256 | Submission Open
Keywords: glycosaminoglycans; inflammation; infectious disease; cancer
(This special issue belongs to the Section Biochemistry)
Genetic and Molecular Mechanisms of Resistance or Adaptation to Abiotic Stress in Plants
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 4997 | Submission Open
(This special issue belongs to the Section Molecular Plant Sciences)
Traumatic Brain Injury/Chronic Traumatic Encephalopathy as Cause of Alzheimer’s Disease: Physics and Molecular Biology in the Genesis of Neurodegeneration?
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 4940 | Submission Open
Keywords: traumatic brain injury (TBI); chronic traumatic encephalopathy (CTE); head impacts; Alzheimer's disease (AD); neurodegeneration
(This special issue belongs to the Section Molecular Neurobiology)
Advances in Molecular Biology and Treatment of Thymic Epithelial Tumors
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 4934 | Submission Open
Keywords: thymic epithelial tumors; thymomas; tumor biology; pathogenesis; carcinogenesis; biomarkers; tumor microenvironment; targeted therapy; predictive markers
(This special issue belongs to the Section Molecular Oncology)
Blood-Brain Barrier in Neuroinflammation and Neurological Diseases
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 4923 | Submission Open
Keywords: blood-brain barrier; in vitro model; in vivo model; pathology; blood– spinal cord barrier; blood– CSF barrier; blood– nerve barrier; multiple sclerosis; neuromyelitis optica; Alzheimer’ s disease; Parkinson’ s disease; collagen disease; autoimmune encephalitis; amyotrophic lateral sclerosis; trauma; diabetes; cerebral small vessel disease; neuropathic pain; autoimmune neuropathy
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Pathophysiology of Lung Diseases
edited by and Brenda M. Juan-Guardela
submission deadline 20 Sep 2024 | 2 articles | Viewed by 4740 | Submission Open
Keywords: biomarkers; asthma; COPD; pulmonary fibrosis; post-COVID-19 interstitial lung disease; pathogenesis; personalized medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Current Research in Antimicrobial Natural Products
edited by Jose Javier Sanz Gomez
submission deadline 20 Sep 2024 | 3 articles | Viewed by 4730 | Submission Open
Keywords: natural products; chemical composition; spoilage microorganisms; pathogens; food preservatives; biofilms; safety assessment; clean label; antibiotics resistance
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Thyroid Hormone and Molecular Endocrinology
edited by
submission deadline 20 Sep 2024 | 4 articles | Viewed by 4612 | Submission Open
Keywords: hormonal regulation; gene expression: thyroid hormone; therapeutic; thyroid hormone receptors; diabetes; obesity; hyperlipidemia; T3
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Predictive, Prognostic Biomarkers and Therapeutic Targets of Breast Cancer
edited by Antonella Ciabattoni and Fabiana Gregucci
submission deadline 20 Sep 2024 | 4 articles | Viewed by 4607 | Submission Open
Keywords: radiotherapy; breast cancer; stereotactic body radiotherapy; brain radiosurgery; target therapy; immunotherapy; tailored systemic therapy
(This special issue belongs to the Section Molecular Oncology)
New Insights into Lactoferrin
edited by and
submission deadline 20 Sep 2024 | 4 articles | Viewed by 4567 | Submission Open
Keywords: lactoferrin; lactoferrin structure; lactoferrin functions; infection; inflammation; iron homeostasis; oxidative stress; lactoferrin bioavailability
(This special issue belongs to the Section Molecular Immunology)
Molecular Research on Viral Infection and Host Immunity
edited by Helder I. Nakaya
submission deadline 20 Sep 2024 | 2 articles | Viewed by 4548 | Submission Open
Keywords: systems immunology; viral infection; host immunity; single-cell analysis; host-pathogen interactions; transcriptomics; proteomics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Inflammatory Bowel Disease: Molecular Insights
edited by
submission deadline 20 Sep 2024 | 4 articles | Viewed by 4373 | Submission Open
Keywords: genomic sequencing; microbiome; dysbiosis; commensal flora; omics; immunobiology; colitis; Crohn’ s disease; ulcerative colitis; multiomics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms of Pregnancy Complications submission deadline 20 Sep 2024 | 3 articles | Viewed by 4087 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Research on Neurogenesis: 3rd Edition submission deadline 20 Sep 2024 | 3 articles | Viewed by 3976 | Submission Open
Keywords: adult neurogenesis; neurodegeneration; aging; psychiatric disorders; cognition; regeneration; adult neurogenesis evolution
(This special issue belongs to the Section Molecular Neurobiology)
Advances in Glioblastoma: Bridging Genetics, Epigenetics, Immunology and Pathophysiology to Advanced Therapies
edited by Felix Mircea Brehar and Alexandru Vladimir Ciurea
submission deadline 20 Sep 2024 | 1 articles | Viewed by 3801 | Submission Open
Keywords: glioblastoma (GBM); therapeutic resistance; immunological responses; biomarkers; genetic mutations; epigenetic modifications; pathophysiological conditions; tumor microenvironment; drug delivery; targeted therapies
(This special issue belongs to the Section Molecular Oncology)
New Research on Complexes of Nanoparticles and Bioreceptors: Obtaining, Characterization and Applications
edited by and Yi Wan
submission deadline 20 Sep 2024 | 1 articles | Viewed by 3779 | Submission Open
Keywords: nanoparticles; nanozymes; fluorescent nanoparticles; aggregates of nanoparticles; antibody; aptamer; nanoparticle– bioreceptor conjugates; protein corona; nanoparticle-based biosensors; enhanced immunoassays; isothermal amplification; nanoparticle-based therapy; nanoparticle-based delivery; nanotheranostics
(This special issue belongs to the Section Molecular Nanoscience)
Polymeric Materials for Biomedical Applications, Drug and Gene Delivery
edited by
submission deadline 20 Sep 2024 | 4 articles | Viewed by 3776 | Submission Open
Keywords: biodegradable polymers; polyesters; scaffolds; tissue engineering; drug delivery; gene delivery; functional materials; biomedical application
(This special issue belongs to the Section Macromolecules)
Bioprocesses and Biotechnology Related to Extremophiles—Molecular Aspects submission deadline 20 Sep 2024 | 4 articles | Viewed by 3684 | Submission Open
Keywords: waste circularity; plastic recycle; lignocellulose; extremozymes; microbial ecology; microbial bioprocess
(This special issue belongs to the Section Molecular Microbiology)
Molecular Computational Research in Pharmacological and Toxicological Issues
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 3683 | Submission Open
Keywords: in silico study; computational toxicology; adverse drug reaction; drug discovery; QSAR analysis; machine learning; artificial intelligence
(This special issue belongs to the Section Molecular Informatics)
Immunotherapy in Cancer: Molecular Basis and Novel Therapeutic Approaches
edited by Yonggu Lee
submission deadline 20 Sep 2024 | 2 articles | Viewed by 3649 | Submission Open
Keywords: cellular immunotherapy; adoptive immunotherapy; chimeric antigen receptor T-cell; epigenetic modulation; immunometabolism; microbiome; immune checkpoint inhibitor; cancer vaccine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cell Division: A Focus on Molecular Mechanisms
edited by Stefano Sechi and Antonino Colanzi
submission deadline 20 Sep 2024 | 3 articles | Viewed by 3596 | Submission Open
Keywords: cell cycle; cell division; post-translational modification (PTM); mitosis/meiosis; cell organelles; cytokinesis; membrane trafficking; disease; therapeutic target; model organisms
(This special issue belongs to the Section Molecular Biology)
Current Advances in Novel Antiviral Drugs
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 3468 | Submission Open
Keywords: broad-spectrum antivirals; antiviral mechanisms; non-nucleoside antivirals; antiviral resistance; emerging viruses
(This special issue belongs to the Section Molecular Pharmacology)
New Insights into Anti-cancer Drug Discovery and Development
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 3436 | Submission Open
Keywords: anti-cancer drug resistant; cancer recurrence; cancer metastasis; cancer stem cells; target validation; target identification; metabolic reprogramming of cancer stem cells; unmet medical needs
(This special issue belongs to the Section Molecular Pharmacology)
Pharmacogenomics, 3rd Edition
edited by
submission deadline 20 Sep 2024 | 3 articles | Viewed by 3417 | Submission Open
Keywords: pharmacogenomics of cardiovascular disorders; pharmacogenomics of cancer; pharmacogenomics of brain disorders; pharmacogenomics of metabolic and endocrine disorders; pharmacogenomics of gastrointestinal disorders; pharmacogenomics of lipid metabolism disorders; pharmacoepigenomics of pain; pharmacogenomics of psychotropic drugs; neurodegenerative disorders (Alzheimer; Parkinson; multiple sclerosis)
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanism in Neurodegeneration
edited by Milena Atanasova and
submission deadline 20 Sep 2024 | 3 articles | Viewed by 3270 | Submission Open
Keywords: abnormal protein dynamics with misfolding; defective degradation; proteasomal dysfunction and aggregation; often with actions and mutations of molecular chaperones; oxidative stress (OS) and formation of free radicals/reactive oxygen species (ROS)
(This special issue belongs to the Section Molecular Neurobiology)
Calcium Homeostasis of Cells in Health and Disease 2.0 submission deadline 20 Sep 2024 | 2 articles | Viewed by 3234 | Submission Open
Keywords: Ca2+; calcium homeostasis; calcium-binding proteins; aging; disease
(This special issue belongs to the Section Biochemistry)
Advances in the Pathogenesis of Diabetic Kidney Disease: Second Edition submission deadline 20 Sep 2024 | 2 articles | Viewed by 3221 | Submission Open
Keywords: diabetic kidney disease; diagnosis; pathogenesis; treatment; molecular mechanisms; chronic kidney disease; end-stage renal disease; inflammation; oxidative stress; glycemia
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research and Treatment of Breast Cancer: 3rd Edition
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 3168 | Submission Open
Keywords: biomarkers; breast cancer; cancer stem cells; cell signaling; circulating tumor cells; drug discovery; molecular diagnostics; molecular profiling; targeted therapy; therapy resistance
(This special issue belongs to the Section Molecular Oncology)
Gastrointestinal: Inflammation, Immunity and Cancer Pathways
edited by
submission deadline 20 Sep 2024 | 1 articles | Viewed by 3158 | Submission Open
Keywords: inflammation and cancer biology; infectious agents; post-translational modification; signaling pathway; apoptosis; autophagy; necrosis; necroptosis; innate immunity; host– pathogens interactions; cell proliferation; tumor microenvironment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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