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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Editorial Board Members’ Collection Series: “Selenium and Sulfur Chemistry”

edited by

Claudio Santi

and

Narimantas K. Cenas

submission deadline 20 Oct 2025 | 3 articles | Viewed by 8788 | Submission Open

Keywords: selenium; sulfur; redox; catalysis; selenoproteins; green chemistry; materials; stereoselective synthesis

(This special issue belongs to the Section Biochemistry)

The Role of Mesenchymal Stem Cells in Organ Repair and Tissue Regeneration

edited by

Sara Cruciani

submission deadline 20 Oct 2025 | 6 articles | Viewed by 8780 | Submission Open

Keywords: stem cells; differentiation; cell therapy; tissue regeneration; cell mechanisms; regenerative medicine; immunomodulation

(This special issue belongs to the Section Molecular Biology)

Molecular Research and Treatment of Prostate Cancer

edited by

Manuela Zavatti

and

Sandra Marmiroli

submission deadline 20 Oct 2025 | 3 articles | Viewed by 8492 | Submission Open

Keywords: prostate cancer; PI3K/AKT pathway; resistance mechanism; androgen receptor; MAPK

(This special issue belongs to the Section Molecular Oncology)

Novel Extracellular Vesicle-Based Therapy for Central Nervous System Diseases

edited by Andrea Cabrera-Pastor

submission deadline 20 Oct 2025 | 2 articles | Viewed by 7955 | Submission Open

Keywords: extracellular vesicles (EVs); exosomes; therapy; CNS disorders; neuroinflammation; signal transduction; mechanism; interorgan crosstalk; biomarker; EVs from MSCs; drug delivery

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research and Treatment in Multiple Sclerosis

edited by Nada Starčević Čizmarević and

Borut Peterlin

submission deadline 20 Oct 2025 | 4 articles | Viewed by 7943 | Submission Open

Keywords: multiple sclerosis; neuroinflammation; neurodegeneration; genetics; molecular research; biomarkers; neuroimaging; therapy

(This special issue belongs to the Section Molecular Biology)

New Insights into Liver Biology and Disease Pathogenesis: Shedding Light on Novel Diagnostic and Therapeutic Approaches

edited by

Thiago Almeida Pereira

submission deadline 20 Oct 2025 | 5 articles | Viewed by 7792 | Submission Open

Keywords: liver molecular biology; novel biomarkers; liver regeneration; liver repair; liver carcinogenesis; brain– gut– liver axis; novel therapeutic targets; molecular diagnostic tools; host– pathogen interactions; novel in vitro and in vivo models of liver diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Design, Synthesis, and Bioapplications of Multifunctional Materials

edited by

Raluca Nicoleta Darie-Nita

and

Anamaria Irimia

submission deadline 20 Oct 2025 | 3 articles | Viewed by 7476 | Submission Open

Keywords: bioactivity; biodegradability; polymers; composite materials; (nano)structured materials; packaging; biological and biomedical materials

(This special issue belongs to the Section Materials Science)

Oxidation in Human Health and Disease

edited by

Isabel Fort

submission deadline 20 Oct 2025 | 3 articles | Viewed by 7399 | Submission Open

Keywords: oxidative stress; oxidative balance; biochemical markers; reactive oxygen species TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Molecular Immunology)

Advanced Research in Plant–Fungus Interactions: Second Edition

edited by

Jiangyun Gao

submission deadline 20 Oct 2025 | 3 articles | Viewed by 7385 | Submission Open

Keywords: plant– fungus interactions; symbiotic association; endophytes; plant conservation; mycorrhizal symbioses

(This special issue belongs to the Section Molecular Plant Sciences)

Plant Resilience: Insights into Abiotic and Biotic Stress Adaptations

edited by

Xujun Zhu

submission deadline 20 Oct 2025 | 5 articles | Viewed by 7197 | Submission Open

Keywords: plants; basis of life; environmental stress; complex responses; molecular mechanisms; abiotic and biotic stress adaptations

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanism in Cardiovascular Pathology

edited by Andrea Marzullo

submission deadline 20 Oct 2025 | 5 articles | Viewed by 7105 | Submission Open

Keywords: cardiovascular diseases; molecular biology; sudden death; cardiomyopathies; heart failure; coronary artery diseases; pericarditis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Gynecologic Oncology: Molecular Mechanisms and Therapies

edited by

Angel Yordanov

submission deadline 20 Oct 2025 | 3 articles | Viewed by 6770 | Submission Open

Keywords: cervical cancer; endometrial cancer; ovarian cancer; vulvar cancer; carcinogenesis; microinvairment; immunotherapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Skin Diseases: 3rd Edition

edited by

Naoko Kanda

submission deadline 20 Oct 2025 | 3 articles | Viewed by 6723 | Submission Open

Keywords: infection; inflammation; molecular; neoplasm; pathogenesis; skin diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Heat Shock Proteins: From Molecular Mechanisms to Therapeutics: 2nd Edition

edited by

Gregory Blatch

submission deadline 20 Oct 2025 | 2 articles | Viewed by 6706 | Submission Open

Keywords: heat shock proteins; molecular chaperones; co-chaperones; protein folding; chronic diseases; infectious diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Cancer and Molecular Imaging

edited by Mi-Ae Park

submission deadline 20 Oct 2025 | 3 articles | Viewed by 6704 | Submission Open

Keywords: molecular imaging; radiology; cancer detection; precision medicine; cancer mechanisms

(This special issue belongs to the Section Molecular Biology)

Cutting-Edge Methods for Exploiting Bioactive Compounds in Biomasses: From the Plant Matrix to Molecular Function

edited by Chiara Magni

submission deadline 20 Oct 2025 | 5 articles | Viewed by 6612 | Submission Open

Keywords: plant matrix; agri-food biomasses; biochemistry; bioactive compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Zebrafish as a Model for Biomedical Studies—2nd Edition

edited by

Pierre-Olivier Angrand

submission deadline 20 Oct 2025 | 4 articles | Viewed by 6597 | Submission Open

Keywords: zebrafish; cancer; metabolic diseases; neurological disorders; infectious diseases; xenografts; drug discovery

(This special issue belongs to the Section Molecular Biology)

Pathophysiology and Pharmacology in Psychiatry

edited by

Galila Agam

submission deadline 20 Oct 2025 | 3 articles | Viewed by 6587 | Submission Open

Keywords: psychiatric disorders; mental health; pathophysiology; neuropsychopharmacology; brain

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Pathways and Therapeutic Strategies for Fibrotic Conditions

edited by

Morena Scotece

submission deadline 20 Oct 2025 | 3 articles | Viewed by 6570 | Submission Open

Keywords: fibrosis; fibrotic disorders; autoimmune diseases; cancer; adipose tissue fibrosis; repurposed drugs; gene therapies; cytokine-mediated pathways; anti-fibrotic therapies; systemic diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Insights in Multiple Sclerosis (MS) and Neuroimmunology: 2nd Edition

edited by

Michael C. Levin

submission deadline 20 Oct 2025 | 6 articles | Viewed by 6449 | Submission Open

Keywords: neurodegeneration; neuroimmunology; macrophage; T-cell; B-cell; antibody; neurons; oligodendrocytes; axon; axonal damage; cell death; multiple sclerosis

(This special issue belongs to the Section Molecular Immunology)

Molecular Advances in Functional Products for Health Prevention and Promotion

edited by

Aneta Koronowicz

submission deadline 20 Oct 2025 | 2 articles | Viewed by 6382 | Submission Open

Keywords: functional foods; food fortification; biofortification; bioactive food ingredients; human nutrition; nutrition and immunity; health prevention; chronic non-communicable diseases; epigenetics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Macrophage Polarization: Learning to Manage It (4th Edition)

edited by

Nadia Lampiasi

submission deadline 20 Oct 2025 | 2 articles | Viewed by 6242 | Submission Open

Keywords: macrophages; macrophage plasticity; macrophage polarization; innate immunity; IFN-γ ; TNF-α ; immunomodulators; diseases; homeostasis; inflammation; cancer

(This special issue belongs to the Section Molecular Immunology)

Cell Motility and Its Underlying Cellular and Molecular Mechanisms

edited by

Maria Giulia Lionetto

submission deadline 20 Oct 2025 | 2 articles | Viewed by 6223 | Submission Open

Keywords: cell motility; cell migration; cytoskeleton; adhesion; signaling; imaging; microscopy; molecular biology

(This special issue belongs to the Section Biochemistry)

Neurodegenerative Disease: Looking for Oxidative Stress and Inflammation Mechanisms

edited by

Soraya L. Valles

submission deadline 20 Oct 2025 | 3 articles | Viewed by 6183 | Submission Open

Keywords: neurodegenerative disease; oxidative stress; inflammation mechanisms; neurons; astrocytes; microglia; oligodendroglia

(This special issue belongs to the Section Molecular Neurobiology)

Extracellular Vesicles: The Biology and Therapeutic Applications, 2nd Edition

edited by

Tamás Visnovitz

submission deadline 20 Oct 2025 | 2 articles | Viewed by 6125 | Submission Open

Keywords: extracellular vesicles (EVs); exosomes; release; uptake; bio-distribution; methods; biomarkers; therapeutic applications

(This special issue belongs to the Section Molecular Biology)

Biological Activities and Structure–Activity Relationships of Natural and Non-Natural Compounds

edited by

Eleonora Russo

submission deadline 20 Oct 2025 | 2 articles | Viewed by 6023 | Submission Open

Keywords: natural compounds; synthetic compounds; biological activities; structure– activity relationship (SAR); bioavailability; toxicity; computational modeling; drug delivery; nanomedicine

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Aspects of Cartilage Biology

edited by

Michela Geminiani

submission deadline 20 Oct 2025 | 3 articles | Viewed by 5975 | Submission Open

Keywords: cartilage biology; tissue regeneration; molecular mechanisms; chondrocytes; cartilage disorders; therapeutic interventions; biomaterials

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms and Treatment of Migraine

edited by Noboru Imai

submission deadline 20 Oct 2025 | 1 articles | Viewed by 5960 | Submission Open

Keywords: migraine; nitric oxide synthase (NOS); neuropeptides; calcitonin gene-related peptide (CGRP); pituitary adenylate cyclase activating polypeptide (PACAP); molecular pathways; therapeutic targets; neurovascular condition

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Macrophages in Cancers

edited by

Pierre Tennstedt

submission deadline 20 Oct 2025 | 4 articles | Viewed by 5881 | Submission Open

Keywords: tumor-associated macrophages; tumor microenvironment; monocytes; cancer; cancer therapy; bisphosphonates; cytokines; chemokines; immune response; therapeutic resistance; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Bioprinting: Progress and Challenges

edited by

Rui Vitorino

submission deadline 20 Oct 2025 | 1 articles | Viewed by 5859 | Submission Open

Keywords: advances in 3D bioprinting technologies; biomaterials for bioprinting; bioprinting applications in tissue engineering and regenerative medicine; cellular and molecular interactions in bioprinted constructs; bio-printed organ and tissue models for disease research

(This special issue belongs to the Section Materials Science)

Molecular Research in Rheumatoid Arthritis

edited by Ângelo Calado

submission deadline 20 Oct 2025 | 2 articles | Viewed by 5827 | Submission Open

Keywords: rheumatoid arthritis; synovium; autoimmunity; rheumatology; omics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Heart Diseases: Molecular Pathogenesis, Biomarkers and Therapies

edited by

Nadia Aspromonte

submission deadline 20 Oct 2025 | 3 articles | Viewed by 5761 | Submission Open

Keywords: heart diseases; biomarkers; molecular pathways; personalized medicine; interventional therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Macrophages and Inflammation

edited by

Julia Kzhyshkowska

submission deadline 20 Oct 2025 | 1 articles | Viewed by 5579 | Submission Open

Keywords: innate immunity; transcriptional programs; epigenetics; immunometabolism; receptors; scavenging; cytokines; ROS

(This special issue belongs to the Section Molecular Immunology)

Newer Pharmacological Treatment Concepts for Patients with Acute Coronary Syndrome

edited by

Dimitrios Patoulias

submission deadline 20 Oct 2025 | 2 articles | Viewed by 5577 | Submission Open

Keywords: acute coronary syndrome (ACS); molecular studies; antiplatelet; anticoagulant drugs; lipid-lowering therapies

(This special issue belongs to the Section Molecular Pharmacology)

Hormone/Receptor System in Human Diseases

edited by

Elena Zocchi

submission deadline 20 Oct 2025 | 2 articles | Viewed by 5559 | Submission Open

Keywords: characteristics of hormones; mechanisms of hormone action; structure; subunits and complexes of receptors; receptor function; expression and regulation; hormone/receptor signaling; interactions between receptors and hormones

(This special issue belongs to the Section Molecular Pharmacology)

Mitochondrial Metabolism Alterations in Health and Disease: 2nd Edition

edited by

Vincenza Dolce

Rosita Curcio

and

Graziantonio Lauria

submission deadline 20 Oct 2025 | 2 articles | Viewed by 5553 | Submission Open

Keywords: mitochondrial Metabolism; mitochondrial disorders; cellular processes; dysregulation organisms’ physiology

(This special issue belongs to the Section Biochemistry)

Small Cell Lung Cancer Entering the Sphere of Personalized Treatment

edited by

Anna Grenda

, Michał Szczyrek and Izabela Chmielewska

submission deadline 20 Oct 2025 | 2 articles | Viewed by 5531 | Submission Open

Keywords: small cell lung cancer; SCLC; pathological subtypes; molecular subtypes; DNA; RNA; NGS; next-generation sequencing transcriptome; mutations; molecular analysis

(This special issue belongs to the Section Molecular Oncology)

Amyotrophic Lateral Sclerosis (ALS): Pathogenesis and Treatments

edited by

Monica Consonni

and

Stefania Marcuzzo

submission deadline 20 Oct 2025 | 2 articles | Viewed by 5527 | Submission Open

Keywords: amyotrophic lateral sclerosis; therapeutic applications; extracellular-vesicles; gene variants; RNA metabolism; mitochondrial dysfunction; oxidative stress; neuroinflammation; protein misfolding; muscle impariment

(This special issue belongs to the Section Molecular Neurobiology)

Recent Research on Novel Lipid-Based Nano Drug Delivery Systems

edited by

Eder Lilia Romero

submission deadline 20 Oct 2025 | 2 articles | Viewed by 5279 | Submission Open

Keywords: lipids; nanoparticle; nanovesicle; algae; archaea; plant; bacteria; natural product

(This special issue belongs to the Section Molecular Pharmacology)

New Insights into Plant and Insect Interactions (Second Edition)

edited by

Yonggen Lou

and Xiaoling Sun

submission deadline 20 Oct 2025 | 5 articles | Viewed by 5265 | Submission Open

Keywords: plant defense responses; elicitors; effectors; defense-related signaling; insect– plant interactions; tritrophic interactions; detoxification; defensive compounds; defensive genes

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research on Diabetes—2nd Edition

edited by

Alessandra Puddu

and

Davide Maggi

submission deadline 20 Oct 2025 | 3 articles | Viewed by 5239 | Submission Open

Keywords: diabetes; insulin; glucose metabolism; oxidative stress

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Metabolic Diseases and Genetic Variants

edited by Rajkumar Dorajoo

submission deadline 20 Oct 2025 | 2 articles | Viewed by 5196 | Submission Open

Keywords: genetic variants; DNA sequencing; metabolic disease; whole exome sequencing; quantitative trait loci; fine-mapping; epidemiology; omics; T2D; obesity

(This special issue belongs to the Section Molecular Genetics and Genomics)

Recent Advances in Photocatalysis: An Innovation in Catalysis

edited by

Andreea L. Chibac-Scutaru

submission deadline 20 Oct 2025 | 2 articles | Viewed by 5164 | Submission Open

Keywords: semiconducting nanostructures; photocatalyst immobilized on substrates; hybrid composites; metal-free photocatalyst; photocatalysis mechanism; pollutant removal; hydrogen production; organic synthesis

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Cell Pathways Underlying Neuronal Differentiation

edited by

Michela Ferrucci

submission deadline 20 Oct 2025 | 2 articles | Viewed by 5119 | Submission Open

Keywords: neural progenitor cells; neuronal cell lines; induced pluripotent stem cells; neuronal phenotype; brain tumor cells

(This special issue belongs to the Section Molecular Neurobiology)

Hormone Replacement Therapy

edited by

Marco Antonio Botelho

and

Raouf A. Khalil

submission deadline 20 Oct 2025 | 1 articles | Viewed by 5099 | Submission Open

Keywords: hormone replacement therapy; molecular insights; endocrine signaling; precision medicine; gene expression; epigenetics; non-coding RNAs; personalized regimens

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Mechanism and Treatment Progress of Liver Disease

edited by Yohei Shirakami

submission deadline 20 Oct 2025 | 3 articles | Viewed by 5074 | Submission Open

Keywords: liver diseases; MASLD; alcoholic liver disease; liver cancer; viral hepatitis; sarcopenia

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Virus Engineering and Applications: 3rd Edition

edited by

Laura Menotti

submission deadline 20 Oct 2025 | 3 articles | Viewed by 4977 | Submission Open

Keywords: virus engineering; oncolytic virotherapy; immunovirotherapy; viral biotechnology

(This special issue belongs to the Section Molecular Microbiology)

Perspectives of Molecular Genetics and Genomics in Human Mendelian Diseases

edited by

Marta Rusmini

submission deadline 20 Oct 2025 | 3 articles | Viewed by 4898 | Submission Open

Keywords: functional genomics; omics; genetic disease; human; molecular mechanisms; genome editing; biomarkers; computational genomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Protein Biosensors

edited by

Antonio Varriale

and

Maria Staiano

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4893 | Submission Open

(This special issue belongs to the Section Biochemistry)

Neuroprotective Effects of Food Ingredients

edited by

Elena Ibáñez

and

Alejandro Cifuentes

submission deadline 20 Oct 2025 | 3 articles | Viewed by 4876 | Submission Open

Keywords: neuroprotection; Parkinson; Alzheimer; bioactive compounds; agri-food by-products; chemical characterization; foodomics; metabolomics; molecular mechanisms

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Displaying special issue 51-100 on page 2 of 70.

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