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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Oxidative Stress and Mitochondrial Dysfunction
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1277
Keywords: oxidative/nitrosative stress; mitochondrial dysfunction; gene and protein expressions; neuroinflammation; stroke; traumatic brain injury; Alzheimer’ s disease; Parkinson’ s disease; amyotrophic lateral sclerosis; multiple sclerosis; acute and chronic neurodegenerations
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Selected Papers from the International Conference on Plant Systems Biology submission deadline 30 Apr 2024 | 1 articles | Viewed by 1273
Keywords: abiotic and oxidative stress; bioinformatics and computational modeling; genetics and genomics; molecular breeding; plant biotechnology; molecular biology; plant systems biology
(This special issue belongs to the Section Molecular Plant Sciences)
Artificial Intelligence/ML in Molecular Cancer Research
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1247
Keywords: artificial intelligence; machine learning; deep learning; cancer; multi-omics analysis; statistical methods
(This special issue belongs to the Section Molecular Informatics)
Molecular Advances in Dental Pulp Tissue Engineering 2.0 submission deadline 30 Apr 2024 | 1 articles | Viewed by 1239
Keywords: tissue engineering and regenerative medicine (TERM); pulp regeneration; scaffold materials; stem cells; bioactive molecules; dentin matrix proteins
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Adipokines as Peripheral Signals for the Integration of Energy Balance and Reproduction submission deadline 30 Apr 2024 | 1 articles | Viewed by 1233
Keywords: adipokines; obesity; fertility; reproduction; hypothalamic– pituitary– gonadal axis
(This special issue belongs to the Section Biochemistry)
Mitochondrial Dysfunction in Aging and Diseases Affecting the Neuromuscular System
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1202
Keywords: mitochondrial physiology; mitochondria in ALS; mitochondria in SMA; mitochondria in neuroinflammation; mitochondria in muscular dystrophy; mitochondria in sarcopenia; mitochondria in myasthenia gravis; mitochondria in muscle physiology; mitochondria and motoneurons; mitochondria and therapy
(This special issue belongs to the Section Biochemistry)
Interactions between the Environment and the Intestinal Epithelium: Gut Barrier Function and Inflammation submission deadline 30 Apr 2024 | 1 articles | Viewed by 1196
Keywords: advances on the environmental factors including nano- and micro-particles and pesticides; food additives; microbiota metabolites with anti- or pro-inflammatory properties; intestinal permeability; intestinal stem cells
(This special issue belongs to the Section Molecular Immunology)
Neuropeptides and Neurological Diseases
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1193
Keywords: somatostatin receptors; ghrelin receptors; cortistatin; neuroendocrine and immune systems; neurodegeneration; cardiovascular; tumors; intracellular signaling
(This special issue belongs to the Section Molecular Neurobiology)
Insights into the Mechanisms and Driving Forces of Biomolecular Adsorption Processes
edited by Ana Cristina Dias-Cabral and Paula Fraga-García
submission deadline 30 Apr 2024 | 2 articles | Viewed by 1181
Keywords: biomolecule adsorption; biomolecule separation; interaction mechanisms; driving forces; biophysical studies; interaction thermodynamics; downstream processing; materials and surface science; interfacial chemistry
(This special issue belongs to the Section Molecular Biophysics)
Editorial Board Members’ Collection Series: “Molecular Dynamics” submission deadline 30 Apr 2024 | 1 articles | Viewed by 1118
Keywords: quantum mechanics; classical mechanics; hybrid QM/MM; molecular dynamics at the atomic level; steered molecular dynamics; coarse-graining; docking(protein– protein; protein– ligand); the molecular dynamics of protein– ligand interactions; drug design; virtual screening
(This special issue belongs to the Section Molecular Biophysics)
Molecular Immunity and Defense: Oral and Periodontal Health
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1117
Keywords: periodontal pathology; implant mucositis; peri impalntitis; root fracture; endodontic lesion
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Inflammatory Responses and Immunity under Stress
edited by Judith-Irina Buchheim
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1110
Keywords: psychoneuroimmunology; immunity; stress-modulated immune response; autoimmunity; hypersensitivity; stressors; environmental stress; allostatic load; autonomic nervous system (ANS); hypothalamic– pituitary– adrenal (HPA) axis
(This special issue belongs to the Section Molecular Immunology)
New Insights into Proteomics and Applications in Molecular Diagnostics and Systems Biology
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1079
Keywords: mass spectrometry; liquid chromatography; tandem mass spectrometry (MS/MS); quantitative proteomics; shotgun proteomics; label-free quantification; post-translational modifications; protein– protein interactions; proteogenomics; single-cell proteomics; data analysis; bioinformatics; functional proteomics; phosphoproteomics; glycoproteomics; biomarker discovery; top– down proteomics; clinical applications; disease proteomics; systems biology
(This special issue belongs to the Section Molecular Informatics)
Molecular Genetics of Human Diseases: Focus on Intestinal Cancers
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1049
Keywords: intestinal cancer; dietary compound; nutrigenomics; DNA methylation; non-coding RNAs; histone modifications; epigenetic changes; gut microbiome; intestinal disease; environmental factors
(This special issue belongs to the Section Molecular Genetics and Genomics)
Cellular Stress and Genomics in Eukaryotes
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1048
Keywords: genomic instability; chromosomal instability; premature mitoses; premature chromosome condensation; cell death; replication stress; DNA damage; cell cycle checkpoints; synthetic lethality; chromothripsis; eukaryotic cells
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanism in Neurodegeneration
edited by Milena Atanasova and
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1018
Keywords: abnormal protein dynamics with misfolding; defective degradation; proteasomal dysfunction and aggregation; often with actions and mutations of molecular chaperones; oxidative stress (OS) and formation of free radicals/reactive oxygen species (ROS)
(This special issue belongs to the Section Molecular Neurobiology)
Research Progress of Tumor Endothelial Cells
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1002
Keywords: tumorigenesis; cancer; metastasis; endothelial cells (ECs); tumor cells; tumor microenvironment; metabolism; proliferation; invasion; vascular; microvascular; tumor angiogenesis; sprouting
(This special issue belongs to the Section Molecular Oncology)
The Plasticity of the Innervation of the Urogenital System
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 984
Keywords: neuronal plasticity; urogenital tract; innervation; nerve growth factors; neuropeptides; neurotrophins; nerve injury; nerve regeneration; pelvic nerves; autonomic nervous system; smooth muscle dysfunction; bladder hyperactivity; erectile dysfunction; vaginal atrophy; neuromodulation
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Advances and Insights into Brain Hypoxia
edited by Natalia N. Nalivaeva
submission deadline 30 Apr 2024 | 1 articles | Viewed by 983
Keywords: hypoxia; ischemia; HIF-1; COVID-19; hypoxic pre- and postconditioning; gene expression; cell death; brain tolerance; neurodegeneraion; neuroprotection
(This special issue belongs to the Section Molecular Neurobiology)
Epigenetic Dysregulation in Cancers: From Mechanism to Therapy
edited by Saverio Candido
submission deadline 30 Apr 2024 | 1 articles | Viewed by 973
Keywords: epigenetics; non-coding RNAs; microRNAs; histone modifications; chromatin remodeling; DNA methylation; 5-methyl-cytosine; biomarkers; cancer; promoter and body methylation
(This special issue belongs to the Section Molecular Oncology)
Endometriosis and Endometriosis-Associated Cancer: Molecular Pathologies, Diagnosis and Therapeutic Strategies
edited by Uri Dior and Tamar Perri
submission deadline 30 Apr 2024 | 1 articles | Viewed by 972
Keywords: endometriosis; ovarian cancer; breast cancer; epigenetics; gene expression
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Animal Experimental Models in Bone Metabolic Disease 2.0
edited by Jose Luis Pérez-Castrillón and
submission deadline 30 Apr 2024 | 1 articles | Viewed by 948
Keywords: animal experimental models; therapeutic targets; pathophysiology; bone metabolic disease
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Bioactive Compounds for the Prevention and Treatment of Human Diseases
edited by Marek Gogacz
submission deadline 30 Apr 2024 | 1 articles | Viewed by 941
Keywords: bioactive compounds; antioxidant activity; inflammation; natural plants and products; macro and microelements; vitamins; immune system; health benefits; anticancer activity; disease prevention
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular and Cellular Mechanisms Underlying Gastrointestinal Diseases
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 900
Keywords: gastrointestinal diseases; liver; pancreas; inflammation bowel diseases; dyspepsia
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mitochondrial Footprint in Neurological Pathology submission deadline 30 Apr 2024 | 1 articles | Viewed by 884
Keywords: neurological disorders; mitochondrial bioenergetics; mitochondrial dynamics; immunometabolism; biomarkers; mitochondrial medicine
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Advances in Circadian Rhythm and Metabolism
edited by Olga Cela and Rosella Scrima
submission deadline 30 Apr 2024 | 1 articles | Viewed by 859
Keywords: circadian rhythms; metabolism; clock genes; protein processing/post-translational modifications; chronomedicine
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Editorial Board Members’ Collection Series: “Neuroinflammation” submission deadline 30 Apr 2024 | Viewed by 832
Keywords: neuroinflammation; amyotrophic lateral sclerosis; multiple sclerosis; Parkinson's disease; Alzheimer's disease; ataxias; traumatic brain injury; spinal cord injury
(This special issue belongs to the Section Molecular Immunology)
Advances in Molecular Studies of Mercury Toxicity
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 819
Keywords: mercury; methylmercury; toxicity; cells; tissues; signaling molecules; molecular determinants; genetic susceptibility; developmental susceptibility
(This special issue belongs to the Section Molecular Toxicology)
The Lysosome in Human Health and Diseases submission deadline 30 Apr 2024 | 1 articles | Viewed by 801
Keywords: lysosomal storage disorders; lysosomal hub; lysosomal signalling; lysosomal trafficking; nutrient sensing; cell death; disease models; biomarkers; RNA-therapeutics
(This special issue belongs to the Section Molecular Biology)
Molecular Research of Gastrointestinal Disease 2.0 submission deadline 30 Apr 2024 | 2 articles | Viewed by 789
Keywords: gastrointestinal health; gastrointestinal disorders; gastrointestinal disease; gastrointestinal homeostasis; molecular targets; mechanisms; pathways; molecular markers; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Computational Simulation of Macromolecular Processes Involved in Disease submission deadline 30 Apr 2024 | 1 articles | Viewed by 768
Keywords: computational biology; virtual modeling; drug discovery; molecular dynamics; molecular mechanism of disease
(This special issue belongs to the Section Molecular Biophysics)
Recent Advances in Organic Chemistry: Molecules Synthesis and Reactions submission deadline 30 Apr 2024 | 1 articles | Viewed by 742
Keywords: bioactive natural products; organocatalysis; photoredox reactions; free-radical reactions; organometallic reactions; organic synthesis
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Thermophilic, Heterotrophic Anaerobes—Recent Advances in Phylogeny and Biotechnology
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 695
Keywords: thermophilic; anaerobe; genetic engineering; biofuels; fine chemicals; enzymes
(This special issue belongs to the Section Molecular Microbiology)
Diagnostic and Therapeutic Advances in the Management of Sepsis and Septic Shock—2nd Edition
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 668
Keywords: antibiotics; biomarkers; blood purification in sepsis; endotoxic shock; imaging; infectious disease; resuscitation; biomarkers; septic shock; sepsis-associated AKI
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Musculoskeletal Disease: From Molecular Basis to Therapy
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 663
Keywords: musculoskeletal diseases; osteoporosis; osteoarthritis; sarcopenia; molecular mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Molecular Research in Interaction of Plants and Fungi
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 660
Keywords: plant-fungi interactions; soil microorganisms; ecosystem processes; crop yield; bioactive compounds; bioremediation; mutualistic relationships; carbon cycle; climate change
(This special issue belongs to the Section Molecular Microbiology)
Molecular Mechanism Underlying Memory Modulated by Emotions and Stress
edited by
submission deadline 30 Apr 2024 | Viewed by 633
Keywords: emotions; stress; memory; pathology
(This special issue belongs to the Section Molecular Neurobiology)
Adenosine Receptors in Health and Disease
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 603
Keywords: adenosine; adenosine receptors; P1 receptors; A1 receptor; A2A receptor; A2B receptor; A3 receptor; adenosine deaminase; adenosine kinase; adenosine transporters; adenosine receptor agonists; adenosine receptor antagonists; caffeine
(This special issue belongs to the Section Molecular Biology)
Advances in Breeding, Genetics, and Genomics of Fruit Crops
edited by Elisa Vendramin and Micali Sabrina
submission deadline 30 Apr 2024 | Viewed by 579
Keywords: genetics; genomics; transcriptomics; plant genetic resources; SNP; SSR; GWAS; QTLs; genomic selections; candidate genes
(This special issue belongs to the Section Molecular Plant Sciences)
Physiological and Biochemical Research on Forest Plants to Improve Abiotic Stress Tolerance submission deadline 30 Apr 2024 | 1 articles | Viewed by 577
Keywords: forests plants; abiotic stress; ecophysiology; genetic analyses; dendrochronology; biochemical analyses
(This special issue belongs to the Section Molecular Plant Sciences)
TRP Channels in Pain and Inflammation 2.0 submission deadline 30 Apr 2024 | 1 articles | Viewed by 548
Keywords: TRP channels; “ thermoTRP” channels; neuropathic pain; inflammatory pain; cancer pain; pruritic skin iseases; itch; neurogenic inflammation; migraine
(This special issue belongs to the Section Molecular Immunology)
Amyloid Hetero-Aggregation 2.0 submission deadline 30 Apr 2024 | Viewed by 526
Keywords: amyloid; co-aggregation; hetero-aggregation; human proteins; bacterial amyloids; viral proteins; cytotoxicity; structure; function
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Research on Diagnostics, Pathogenesis and Novel Therapeutic Tools in Melanoma
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 505
Keywords: melanoma; LC-OCT; early diagnosis; differential diagnosis; genetics; genes; markers
(This special issue belongs to the Section Molecular Oncology)
Ion Channels of Nociception 3.0
edited by
submission deadline 30 Apr 2024 | Viewed by 488
Keywords: pain; nociception; molecular mechanisms; molecular structures; migraine; neuropathic pain; cancer pain; nociceptive neurons; voltage-gated ion channels; ligand-gated ion channels; analgesic drugs; mechanosensitive Piezo channels; CRAC Orai1 channels; K2P channels; sodium channels; sensitization; ion channel inactivation
(This special issue belongs to the Section Biochemistry)
Recent Advances in Epigenetics in Plant Research
edited by and
submission deadline 30 Apr 2024 | 1 articles | Viewed by 423
Keywords: plant; genomics; systematics
(This special issue belongs to the Section Molecular Plant Sciences)
Editorial Board Members’ Collection Series: “Molecular Research in Alzheimer’s Disease” submission deadline 30 Apr 2024 | 1 articles | Viewed by 410
Keywords: Alzheimer’ s disease (AD); molecular underpinnings; neurodegenerative disorder; beta-amyloid accumulation; tau protein phosphorylation; neuroinflammation; oxidative stress; therapeutic targets; biomarkers; early diagnosis; genomic sequencing; proteomic analyses; multidisciplinary approach; prevention; treatment
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Insights into Atherosclerosis and Vascular Endothelial Cells
edited by
submission deadline 30 Apr 2024 | Viewed by 378
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Editorial Board Members’ Collection Series: “Protein Biophysics” submission deadline 30 Apr 2024 | 1 articles | Viewed by 376
Keywords: protein structure and prediction; protein biophysics; protein dynamics; peptide and protein aggregation; protein misfolding; protein folding; protein stability; protein function; posttranslational modifications; intrinsically disordered proteins; protein– ligand interactions; protein– protein interactions; protein– nucleic acid interactions; membrane proteins; liquid– liquid phase separation
(This special issue belongs to the Section Molecular Biophysics)
Pathways in Development and Disease: The Role of RNA Regulation in Biological and Pathological Events submission deadline 30 Apr 2024 | Viewed by 370
Keywords: RNA; human disease; cancer; diagnostic; therapy; development
(This special issue belongs to the Section Biochemistry)
Molecular Mechanisms and Therapeutic Approaches to Osteoarthritis
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 368
Keywords: mode of action; molecular mechanisms; pathogenesis; drug delivery; disease-modifying drug; translational research; cell therapy; regenerative medicine
(This special issue belongs to the Section Molecular Pharmacology)
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