Special Issue "Correlation Analysis Applied to Solvolysis Reactions"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Physical Chemistry, Theoretical and Computational Chemistry".
Deadline for manuscript submissions: closed (15 December 2011)
Prof. Dr. Dennis N. Kevill
Distinguished Research Professor Emeritus, Department of Chemistry and Biochemistry, Northern Illinois University, DeKalb, IL 60115, USA
Interests: reaction mechanism in organic chemistry; solvolysis reactions; solvent nucleophilicity; mechanism of nucleophilic attack at acyl carbon; phosphorus; sulfur
Solvolysis reactions involve the solvent also as a reactant. One technique in their study involves correlation analysis using linear free energy relationships. Grunwald and Winstein developed a scale of solvent ionizing power for unimolecular solvolyses and subsequently a second term, involving nucleophilicity, was added for bimolecular reactions. Originally applied to reactions at a saturated carbon, the approach can also be applied to solvolyses at acyl carbon and at heteroatoms, such as sulfur or phosphorus (Kevill, D.N.; D’Souza, M. J. Sixty years of the Grunwald-Winstein equation: development and recent applications. J. Chem. Res., 2008, 61-66.).
If the interest is more on the nature of the interactions of the substrate with the solvent, rather than reaction mechanism, since there are a number of possibly relevant solvent properties, multiparameter equations will be required. Several books dealing with this area exist. (For example, Shorter, J, Correlation Analysis of Organic Reactivity with Particular Reference to Multiple Regression; Research Studies: New York, 1982).
Contributions in any area of the application of existing correlation equations to new reactions, modification of existing equations, or development of new approaches are welcome.
Prof. Dr. Dennis N. Kevill
- correlation analysis
- linear free energy relationships
- Grunwald-Winstein equation
- multiparameter equations
Article: Correlation of the Rates of Solvolysis of Neopentyl Chloroformate—A Recommended Protecting Agent
Int. J. Mol. Sci. 2011, 12(2), 1161-1174; doi:10.3390/ijms12021161
Received: 6 January 2011; in revised form: 30 January 2011 / Accepted: 9 February 2011 / Published: 15 February 2011| Download PDF Full-text (377 KB) | Download XML Full-text
Int. J. Mol. Sci. 2011, 12(8), 4805-4818; doi:10.3390/ijms12084805
Received: 6 July 2011; in revised form: 22 July 2011 / Accepted: 18 July 2011 / Published: 28 July 2011| Download PDF Full-text (398 KB) | Download XML Full-text
Article: Correlation of the Rates of Solvolysis of i-Butyl Fluoroformate and a Consideration of Leaving-Group Effects
Int. J. Mol. Sci. 2011, 12(11), 7806-7817; doi:10.3390/ijms12117806
Received: 9 September 2011; in revised form: 21 October 2011 / Accepted: 31 October 2011 / Published: 10 November 2011| Download PDF Full-text (153 KB) | Download XML Full-text
Int. J. Mol. Sci. 2011, 12(12), 8316-8332; doi:10.3390/ijms12128316
Received: 19 October 2011; in revised form: 10 November 2011 / Accepted: 14 November 2011 / Published: 28 November 2011| Download PDF Full-text (379 KB) | Download XML Full-text
Article: Use of Linear Free Energy Relationships (LFERs) to Elucidate the Mechanisms of Reaction of a γ-Methyl-β-alkynyl and an ortho-Substituted Aryl Chloroformate Ester
Int. J. Mol. Sci. 2012, 13(1), 665-682; doi:10.3390/ijms13010665
Received: 20 December 2011; in revised form: 5 January 2012 / Accepted: 5 January 2012 / Published: 10 January 2012| Download PDF Full-text (459 KB) | Download XML Full-text
Int. J. Mol. Sci. 2012, 13(2), 2012-2024; doi:10.3390/ijms13022012
Received: 14 December 2011; in revised form: 3 January 2012 / Accepted: 13 January 2012 / Published: 13 February 2012| Download PDF Full-text (333 KB) | Download XML Full-text
Article: Photosensized Controlling Benzyl Methacrylate-Based Matrix Enhanced Eu3+ Narrow-Band Emission for Fluorescence Applications
Int. J. Mol. Sci. 2012, 13(3), 3718-3737; doi:10.3390/ijms13033718
Received: 3 February 2012; in revised form: 14 March 2012 / Accepted: 15 March 2012 / Published: 21 March 2012| Download PDF Full-text (677 KB) | Download XML Full-text | Supplementary Files
Last update: 26 February 2014