Special Issue "Organic Synthesis Using Biocatalyst"
Deadline for manuscript submissions: closed (31 August 2012)
Prof. Dr. Tomoko Matsuda
Tokyo Institute of Technology, Graduate School of Bioscience and Biotechnology, Department of Bioengineering, 4259 Nagatsuta, Midori-ku, Yokohama, 226-850, Japan
Organic synthesis using biocatalysts, especially chiral synthesis, is increasingly getting important for variety of purposes such as drug synthesis and total synthesis due to the high chemo-, region-, and enantio-selectivities of enzyme. More than half of drug candidate molecules have more than one chiral centers and about 10% of the total drug synthesis depends on the biocatalyst. Importantly, these successes are owing to achievements of basic researches. Therefore, this special issue will present novel, unique and innovative application research as well as basic research concerning organic synthesis using biocatalysts. I also hope that this issue will contribute for green chemistry since the enzyme is a natural and reproducible catalyst with high efficiency.
Dr. Tomoko Matsuda
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
- chiral synthesis
- total synthesis
- novel biocatalyst for organic synthesis
- green chemistry
Int. J. Mol. Sci. 2012, 13(6), 7226-7236; doi:10.3390/ijms13067226
Received: 23 April 2012; in revised form: 12 May 2012 / Accepted: 23 May 2012 / Published: 12 June 2012| Download PDF Full-text (412 KB) | Download XML Full-text
Article: Combination of Oxyanion Gln114 Mutation and Medium Engineering to Influence the Enantioselectivity of Thermophilic Lipase from Geobacillus zalihae
Int. J. Mol. Sci. 2012, 13(9), 11666-11680; doi:10.3390/ijms130911666
Received: 25 May 2012; in revised form: 10 August 2012 / Accepted: 20 August 2012 / Published: 17 September 2012| Download PDF Full-text (522 KB) | Download XML Full-text
Article: Optimization of Lipase-Mediated Synthesis of 1-Nonene Oxide Using Phenylacetic Acid and Hydrogen Peroxide
Int. J. Mol. Sci. 2012, 13(10), 13140-13149; doi:10.3390/ijms131013140
Received: 27 July 2012; in revised form: 1 September 2012 / Accepted: 21 September 2012 / Published: 12 October 2012| Download PDF Full-text (441 KB) | Download XML Full-text
Article: Production of (R)-3-Quinuclidinol by E. coli Biocatalysts Possessing NADH-Dependent 3-Quinuclidinone Reductase (QNR or bacC) from Microbacterium luteolum and Leifsonia Alcohol Dehydrogenase (LSADH)
Int. J. Mol. Sci. 2012, 13(10), 13542-13553; doi:10.3390/ijms131013542
Received: 30 August 2012; in revised form: 27 September 2012 / Accepted: 11 October 2012 / Published: 19 October 2012| Download PDF Full-text (320 KB) | Download XML Full-text
Review: Biotransformations Utilizing β-Oxidation Cycle Reactions in the Synthesis of Natural Compounds and Medicines
Int. J. Mol. Sci. 2012, 13(12), 16514-16543; doi:10.3390/ijms131216514
Received: 31 August 2012; in revised form: 19 November 2012 / Accepted: 21 November 2012 / Published: 5 December 2012| Download PDF Full-text (3412 KB) | Download XML Full-text
Last update: 30 August 2012