Special Issue "Molecular Research of Carcinogenesis"
Deadline for manuscript submissions: closed (30 July 2013)
Dr. Laurence Huc
INRA, UMR1331, Toxalim, Research Centre in Food Toxicology, F-31027 Toulouse, France
Interests: proto-oncogenes; tumor suppressor genes; ageing; carcinogens; initiation; promotion; metastasis; oxidative stress; energetic metabolism
Carcinogenesis is a multiparametric process that involves diverse factors such as genetic, environmental or ageing. If data about genetic (proto-oncogenes, tumor suppressors, metastasis suppressors) are quite well-documented, the challenge is now to establish the impact of the environment (chemical, physical, viral) on tumoral progression. Some xenobiotics have deleterious effects on normal cells and then, can initiate cancer transformation and or promote cancer progression. Mutagens, by targeting DNA, have a direct effect on cellular carcinogenesis but many compounds have pleitropic effects, acting on proliferation, apoptosis, cell motility, oxidative stress, energetic metabolism... This special issue will tackle to complex problematic of molecular carcinogenesis and will gather works dealing with the mechanisms involved in chemical, physical and viral carcinogenesis but also ageing-related carcinogenesis and the role of tumour-associated genes.
Dr. Laurence Huc
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
- tumor suppressor genes
- oxidative stress
- energetic metabolism
Int. J. Mol. Sci. 2013, 14(10), 21087-21113; doi:10.3390/ijms141021087
Received: 30 August 2013; in revised form: 27 September 2013 / Accepted: 4 October 2013 / Published: 21 October 2013| Download PDF Full-text (692 KB) | View HTML Full-text | Download XML Full-text
Article: Crosstalk between Beta-Catenin and Snail in the Induction of Epithelial to Mesenchymal Transition in Hepatocarcinoma: Role of the ERK1/2 Pathway
Int. J. Mol. Sci. 2013, 14(10), 20768-20792; doi:10.3390/ijms141020768
Received: 9 July 2013; in revised form: 23 September 2013 / Accepted: 3 October 2013 / Published: 16 October 2013| Download PDF Full-text (1241 KB) | View HTML Full-text | Download XML Full-text
Article: Glycogen Synthase Kinase 3β Inhibition as a Therapeutic Approach in the Treatment of Endometrial Cancer
Int. J. Mol. Sci. 2013, 14(8), 16617-16637; doi:10.3390/ijms140816617
Received: 17 May 2013; in revised form: 19 July 2013 / Accepted: 24 July 2013 / Published: 12 August 2013| Download PDF Full-text (1201 KB) | View HTML Full-text | Download XML Full-text | Supplementary Files
Article: The L10P Polymorphism and Serum Levels of Transforming Growth Factor β1 in Human Breast Cancer
Int. J. Mol. Sci. 2013, 14(8), 15376-15385; doi:10.3390/ijms140815376
Received: 21 June 2013; in revised form: 13 July 2013 / Accepted: 15 July 2013 / Published: 24 July 2013| Download PDF Full-text (773 KB) | View HTML Full-text | Download XML Full-text
Article: Pilot Study of CYP2B6 Genetic Variation to Explore the Contribution of Nitrosamine Activation to Lung Carcinogenesis
Int. J. Mol. Sci. 2013, 14(4), 8381-8392; doi:10.3390/ijms14048381
Received: 14 March 2013; in revised form: 2 April 2013 / Accepted: 9 April 2013 / Published: 16 April 2013| Download PDF Full-text (236 KB) | View HTML Full-text | Download XML Full-text | Supplementary Files
Last update: 18 December 2012