Special Issue "Molecular Research of Carcinogenesis"


A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology".

Deadline for manuscript submissions: closed (30 July 2013)

Special Issue Editor

Guest Editor
Dr. Laurence Huc
INRA, UMR1331, Toxalim, Research Centre in Food Toxicology, F-31027 Toulouse, France
Website: http://www4.toulouse.inra.fr/toxalim_eng/Research-Teams/E9-PPCA-Prevention-Promotion-of-Carcinogenesis-by-Food/Team
E-Mail: laurence.huc@toulouse.inra.fr
Interests: proto-oncogenes; tumor suppressor genes; ageing; carcinogens; initiation; promotion; metastasis; oxidative stress; energetic metabolism

Special Issue Information

Dear Colleagues,

Carcinogenesis is a multiparametric process that involves diverse factors such as genetic, environmental or ageing. If data about genetic (proto-oncogenes, tumor suppressors, metastasis suppressors) are quite well-documented, the challenge is now to establish the impact of the environment (chemical, physical, viral) on tumoral progression. Some xenobiotics have deleterious effects on normal cells and then, can initiate cancer transformation and or promote cancer progression. Mutagens, by targeting DNA, have a direct effect on cellular carcinogenesis but many compounds have pleitropic effects, acting on proliferation, apoptosis, cell motility, oxidative stress, energetic metabolism... This special issue will tackle to complex problematic of molecular carcinogenesis and will gather works dealing with the mechanisms involved in chemical, physical and viral carcinogenesis but also ageing-related carcinogenesis and the role of tumour-associated genes.

Dr. Laurence Huc
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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  • proto-oncogenes
  • tumor suppressor genes
  • ageing
  • carcinogens
  • initiation
  • promotion
  • metastasis
  • oxidative stress
  • energetic metabolism

Published Papers (5 papers)

by , , , , ,  and
Int. J. Mol. Sci. 2013, 14(10), 21087-21113; doi:10.3390/ijms141021087
Received: 30 August 2013; in revised form: 27 September 2013 / Accepted: 4 October 2013 / Published: 21 October 2013
Show/Hide Abstract | Cited by 2 | PDF Full-text (692 KB) | HTML Full-text | XML Full-text

by ,  and
Int. J. Mol. Sci. 2013, 14(10), 20768-20792; doi:10.3390/ijms141020768
Received: 9 July 2013; in revised form: 23 September 2013 / Accepted: 3 October 2013 / Published: 16 October 2013
Show/Hide Abstract | Cited by 3 | PDF Full-text (1241 KB) | HTML Full-text | XML Full-text

by , , , , ,  and
Int. J. Mol. Sci. 2013, 14(8), 16617-16637; doi:10.3390/ijms140816617
Received: 17 May 2013; in revised form: 19 July 2013 / Accepted: 24 July 2013 / Published: 12 August 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (1201 KB) | HTML Full-text | XML Full-text | Supplementary Files

by , , , , ,  and
Int. J. Mol. Sci. 2013, 14(8), 15376-15385; doi:10.3390/ijms140815376
Received: 21 June 2013; in revised form: 13 July 2013 / Accepted: 15 July 2013 / Published: 24 July 2013
Show/Hide Abstract | Cited by 2 | PDF Full-text (773 KB) | HTML Full-text | XML Full-text

by , , ,  and
Int. J. Mol. Sci. 2013, 14(4), 8381-8392; doi:10.3390/ijms14048381
Received: 14 March 2013; in revised form: 2 April 2013 / Accepted: 9 April 2013 / Published: 16 April 2013
Show/Hide Abstract | PDF Full-text (236 KB) | HTML Full-text | XML Full-text | Supplementary Files

Last update: 18 December 2012

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert