The Pathway of Antigen Processing and Presentation

Dear Colleagues,

The human adaptive immune system can sense infected or aberrant cells by detecting small peptides on the cell surface that belong to a pathogen or are generated due to cancerous transformation. These peptides, called antigenic peptides, are generated inside the cell by the specialized pathway of antigen processing and presentation. This pathway continuously samples the protein content of the cell and presents peptides bound onto major histocompatibility complex molecules on the cell surface. This Special Issue will focus on all molecular aspects of this important pathway, their role in health and disease, and their roles in regulating immune responses and efforts to pharmacologically modulate them for therapeutic purposes.

Dr. Efstratios Stratikos
Guest Editor

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