Special Issue "NMR in Medicine"
A special issue of Diagnostics (ISSN 2075-4418).
Deadline for manuscript submissions: closed (30 May 2015)
Dr. Krishan Kumar
Director, Laboratory for Translational Research in Imaging Pharmaceuticals; Ohio State Molecular Imaging Pharmaceutical Scholar; Department of Radiology, The Ohio State University, 460 West 12th Ave, Columbus, OH 43240, USA
Phone: 732 766 5222
Interests: Targeted MRI Contrast Agents, Nano Material Based MRI Contrast Agents, PET Imaging Agents Using Antibodies and Antibody Fragments, and Process Development for PET Radionuclides Production and Separation
Magnetic Resonance Imaging (MRI) has become a routine technique in diagnostics imaging. Millions of MRI procedures are performed every year. It is a safe, non-invasive, and non-destructive tool for imaging soft tissues and for detecting tumors in many organs. Significant progress has been made since the first demonstration of the MRI in the 1970’s; increasingly sophisticated instrumentations and T1 and T2 MRI contrast agents (CAs) have been developed. For example, numerous CAs have become available commercially since the introduction of the first gadolinium-based MRI contrast agent in the 1980s. Subsequently, gadolinium-based CAs have become the subject of a black-box warning from the US FDA. This was due to reported serious side effects, termed Nephrogenic Systemic Fibrosis (NSF), in patients with impaired renal functions. Therefore, recent research has been focused on the development of a newer generation of MRI contrast agents with greater efficiency (high relaxivity), and increased safety (i.e., no loss of gadolinium in vivo) and targeting capability; these developments include several nanoparticle-based technologies.
Hybrid technologies involving PET/CT and SPECT/CT are being used routinely in the clinic with many thousands of scanners being used worldwide, while PET/MR imaging has been recently approved for clinical use. This encourages researchers to investigate the further development of SPECT/MR based technology. This Special Issue will provide a forum for communication among chemists, physicists, biologists, biochemists, and medical practitioners, such a radiologists. The issue will focus on research and review articles related to developments in MRI technologies, novel MRI contrast agents, clinical applications, and pharmacovigilance.
Dr. Krishan Kumar
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. For the first couple of issues the Article Processing Charge (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- Nuclear Magnetic Resonance, NMR
- NMR in Biomedicine
- Magnetic Resonance Imaging, MRI
- Contrast Agents
- MRI Contrast Agents
- Enhanced Relaxivity
- T1 Agents, T2 Agents
- Nanoparticulate-Based MRI Contrast Agents
- PET/MR, SPECT/MR
- Nephrogenic Systemic Fibrosis