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Diagnostics
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Ultrasound Elastography in Diagnosis
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Ultrasound Elastography in Diagnosis

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 2913

Special Issue Editors

Dr. Markus Lerchbaumer

E-Mail Website
Guest Editor
Department of Radiology, Charité University Medicine, Campus Mitte, Charitéplatz 1, 10117 Berlin, Germany
Interests: multiparametric ultrasound; CEUS; US elastography; genitourinary imaging; testicular imaging; interventional ultrasound
Dr. Thomas Fischer

E-Mail Website
Guest Editor
Department of Radiology, Head of the Interdisciplinary US Center and Research Laboratory, Charité University Medicine, Campus Mitte, Charitéplatz 1, 10117 Berlin, Germany
Interests: CEUS; liver imaging; prostate cancer; MRI/US fusion biopsy; breast ultrasound

Special Issue Information

Dear Colleagues,

Diagnostic ultrasound (US) became an integral part in the daily clinical routine used by many different subspecialities. In recent years, technology has evolved and there has been an increase in new ultrasound techniques such as elastography techniques including both parametric shear wave elastography and semiquantitative strain elastography.

US elastography remains a non-invasive imaging technique to determine the stiffness or elasticity of organs and other tissue structures. Established applications are the assessment of parenchymal liver disease and the characterization of breast lesions or thyroid nodules. Besides these established implications in the clinical routine, there are new trends in musculoskeletal imaging (tendon and muscle stiffness evaluation) and genitourinary imaging (assessment of focal testicular lesions). Hence, the numbers of publications has increased rapidly for new indications.

We are pleased to invite you to submit work regarding new aspects and applications for the use of US elastography for tissue characterization or the assessment of focal lesions.

This Special Issue will present the challenges and recent advances in the use of US elastography for diagnosis. Both original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: liver assessment, genitourinary imaging, MSK imaging, head and neck imaging, assessment of focal lesion, and basic research.

We look forward to receiving your contributions.

Dr. Markus Lerchbaumer
Dr. Thomas Fischer
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • elastography
  • multiparametric ultrasound
  • shear-wave elastography
  • strain elastography
  • diagnosis
  • ultrasound imaging

Published Papers (3 papers)

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11 pages, 521 KiB  
Article
Predictors of Early Continence Recovery Following Radical Prostatectomy, Including Transperineal Ultrasound to Evaluate the Membranous Urethra Length (CHECK-MUL Study)
by Bara Barakat, Mustapha Addali, Boris Hadaschik, Christian Rehme, Sameh Hijazi and Samy Zaqout
Diagnostics 2024, 14(8), 853; https://doi.org/10.3390/diagnostics14080853 - 21 Apr 2024
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Abstract
Introduction: To predict early continence recovery following radical prostatectomy (RP) using baseline demographic and clinical data, as well as dynamic transperineal ultrasound (TPUS) parameters of membranous urethral length (MUL). Patients and Methods: A retrospective CHECK-MUL (check of membranous urethral length) study was conducted. [...] Read more.
Introduction: To predict early continence recovery following radical prostatectomy (RP) using baseline demographic and clinical data, as well as dynamic transperineal ultrasound (TPUS) parameters of membranous urethral length (MUL). Patients and Methods: A retrospective CHECK-MUL (check of membranous urethral length) study was conducted. We evaluated 154 patients who underwent RP between August 2018 and April 2023. All patients underwent pre- and postoperative dynamic TPUS to measure MUL. Urinary continence was defined as the use of one safety pad or less 3 months post surgery. The International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) was used to assess urinary incontinence (UI). We used logistic regression to assess the association between MUL and early continence recovery. A multivariable logistic regression model was then constructed for the prediction of early continence recovery based on the MUL. Results: The median MUL observed pre- and postoperatively in this study were similar (14.6 mm and 12.9 mm). In the univariable logistic regression analysis, the pre- and postoperative MUL measured by TPUS (odds ratio (OR): 1.12; 95%-CI: 1.02–1.79; p = 0.05 and OR: 1.01; 95%-CI: 1.02–1.12; p < 0.01) directions were independent predictors of early continence recovery 3 months post surgery. In addition, age (OR: 1.23; 95%-CI: 1.11–1.42; p = 0.03), BMI (OR: 1.44; 95%-CI: 1.18–2.92; p = 0.05), and bilateral nerve sparing (OR: 1.24; 95%-CI: 1.02–1.9; p = 0.05) were independent predictors of urinary continence in univariable logistic regression models. Preoperative MUL >15 mm (95% CI 1.28–1.33; p = 0.03) and postoperative MUL >14 mm (95% CI 1.2–1.16; p = 0.05) were significantly associated with early continence recovery at 3 months post surgery. Conclusions: The likelihood of continence recovery increases with membranous urethral length and decreases with age, BMI, and lack of nerve sparing. Preoperative MUL >15 mm and postoperative MUL >14 mm were significantly associated with early continence recovery at 3 months post surgery. Full article
(This article belongs to the Special Issue Ultrasound Elastography in Diagnosis)
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12 pages, 1154 KiB  
Article
Effect of Physical Parameters and Training Load on Patellar Tendon Stiffness in Professional Athletes
by Claudia Römer, Enrico Zessin, Julia Czupajllo, Thomas Fischer, Bernd Wolfarth and Markus Herbert Lerchbaumer
Diagnostics 2023, 13(15), 2541; https://doi.org/10.3390/diagnostics13152541 - 31 Jul 2023
Cited by 1 | Viewed by 1051
Abstract
Background: Injuries of the patellar tendon commonly occur as a result of mechanical loading of the tendon during physical activity. Shear wave elastography (SWE) is an established technique for assessing tendon stiffness, and has good interindividual reliability. The aim of this study was [...] Read more.
Background: Injuries of the patellar tendon commonly occur as a result of mechanical loading of the tendon during physical activity. Shear wave elastography (SWE) is an established technique for assessing tendon stiffness, and has good interindividual reliability. The aim of this study was to investigate the impacts of physical parameters and different sports on patellar tendon stiffness in professional athletes using SWE. Methods: Standardized patellar tendon SWE was performed in a relaxed supine position with a small roll under the knee (20° flexion) in 60 healthy professional athletes (30 female, 30 male). Multiple linear regression was performed for patellar tendon stiffness including gender, age, body mass index (BMI), and type of sport. Results: Patellar tendon stiffness showed no significant difference between female (3.320 m/s) and male (3.416 m/s) professional athletes. Mean age (female: 20.53 years; male: 19.80 years) and BMI (female: 23.24 kg/m2; male: 23.52 kg/m2) were comparable. Female professional athletes with oral contraceptive (OC) intake showed higher patellar tendon stiffness than athletes without OC intake (3.723 versus 3.017; p = 0.053), but not significantly. Conclusion: In professional athletes, there are no significant differences in patellar tendon stiffness according to gender, age, BMI and type of sport (handball, volleyball, soccer, sprint, hammer throw). Oral contraceptives may not have an impact on patellar tendon stiffness in female athletes. Further studies are necessary. Full article
(This article belongs to the Special Issue Ultrasound Elastography in Diagnosis)
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Other

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13 pages, 722 KiB  
Systematic Review
Associations of Real-Time Ultrasound and Strain and Shear Wave Elastography with Gastrointestinal Organs: A Systematic Review
by Nismat Javed, Haider Ghazanfar, Abhilasha Jyala and Harish Patel
Diagnostics 2023, 13(21), 3302; https://doi.org/10.3390/diagnostics13213302 - 25 Oct 2023
Viewed by 854
Abstract
Ultrasound elastography is gaining attention for its diagnostic potential across various medical fields, and its physical properties make it valuable in modern clinical medicine. However, its specific attributes, especially in the context of recent medical advancements, remain relatively unexplored. This study aimed to [...] Read more.
Ultrasound elastography is gaining attention for its diagnostic potential across various medical fields, and its physical properties make it valuable in modern clinical medicine. However, its specific attributes, especially in the context of recent medical advancements, remain relatively unexplored. This study aimed to identify instrument-specific characteristics and applications of real-time ultrasound elastography, shear wave elastography, and strain elastography, particularly within gastroenterology. Following PRISMA guidelines, the study examined elastography articles on databases like PubMed, resulting in 78 included articles. Data on patient demographics, organ involvement, specificity, sensitivity, accuracy, positive predictive value, and negative predictive value were extracted. Statistical analysis involved SPSS version 21, with significance set at p < 0.05. The majority of patients were male (50.50%), with a mean age of 42.73 ± 4.41 years. Shear wave elastography was the most prevalent technique (48.7%), and liver investigations were predominant in gastroenterology (34.6%). Gastrointestinal applications showed higher sensitivity, positive predictive value, and negative predictive values (p < 0.05) but lower specificity (p < 0.05). Real-time ultrasound elastography exhibited increased specificity, accuracy, and predictive values (p < 0.05). Ultrasound elastography appears more accurate and effective in gastroenterological settings. Nonetheless, its performance depends on instrument-specific and operator-dependent factors. While promising, further studies are necessary to ascertain optimal utilization in both gastrointestinal and non-gastrointestinal conditions. Full article
(This article belongs to the Special Issue Ultrasound Elastography in Diagnosis)
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