The Current Status of Lung Cancer Surgery

A special issue of Current Oncology (ISSN 1718-7729).

Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 2644

Special Issue Editors


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Guest Editor
Thoracic Surgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo F.Vito 1, 00168 Rome, Italy
Interests: lung neoplasm; thymic tumors; mediastinum; thoracic cancer treatments; surgery; non-small cell lung cancer; minimally invasive surgery
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Guest Editor
Thoracic Surgery Unit, Policlinico – San Marco Hospital, University of Catania, Catania, Italy
Interests: lung cancer; thymic tumors; mediastinum; robotic-assisted surgery

Special Issue Information

Dear Colleagues,

Lung cancer remains one of most impactful tumors around the world in terms of incidence, mortality, and society costs.

Surgical treatment is the indicated treatment for early stages, but it also plays a role in the multidisciplinary management of advanced stages, as a therapeutic option in the case of hilar/mediastinal involvement or oligo-metastatic disease.

Moreover, especially in recent years, the development of minimally invasive techniques was permitted to extend some indication in fragile patients and improve post-operative outcomes and the patients’ quality of life.

However, one of the most important points to be clarified regards the impact of surgery on oncological outcomes, and how it should be modulated based on tumor and patient characteristics.

This Special Issue aims to collect studies on the role of lung cancer surgery in terms of post-operative and oncological outcome, with particular interest on peri- and operative management.

Dr. Marco Chiappetta
Dr. Giacomo Cusumano
Guest Editors

Manuscript Submission Information

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Keywords

  • non-small cell lung cancer
  • surgery
  • minimally invasive techniques
  • lung cancer resection
  • complications
  • lung cancer survival

Published Papers (2 papers)

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Editorial

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4 pages, 200 KiB  
Editorial
Surgery for Non-Small Cell Lung Cancer in the Personalized Therapy Era
by Marco Chiappetta, Carolina Sassorossi and Giacomo Cusumano
Curr. Oncol. 2023, 30(8), 7773-7776; https://doi.org/10.3390/curroncol30080563 - 21 Aug 2023
Viewed by 1184
Abstract
Lung cancer remains one of the tumours with the highest incidence and the poorest
prognosis, with an estimated incidence of more than 220,000 cases with 135,000 cancerrelated
deaths annually in the United States [1,2].[...] Full article
(This article belongs to the Special Issue The Current Status of Lung Cancer Surgery)

Research

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17 pages, 283 KiB  
Article
Pneumonectomy for Primary Lung Tumors and Pulmonary Metastases: A Comprehensive Study of Postoperative Morbidity, Early Mortality, and Preoperative Clinical Prognostic Factors
by Konstantinos Grapatsas, Hruy Menghesha, Fabian Dörr, Natalie Baldes, Martin Schuler, Martin Stuschke, Kaid Darwiche, Christian Taube and Servet Bölükbas
Curr. Oncol. 2023, 30(11), 9458-9474; https://doi.org/10.3390/curroncol30110685 - 25 Oct 2023
Viewed by 1104
Abstract
Background: Pneumonectomy is a major surgical resection that still remains a high-risk operation. The current study aims to investigate perioperative risk factors for postoperative morbidity and early mortality after pneumonectomy for thoracic malignancies. Methods: We retrospectively analyzed all patients who underwent pneumonectomy for [...] Read more.
Background: Pneumonectomy is a major surgical resection that still remains a high-risk operation. The current study aims to investigate perioperative risk factors for postoperative morbidity and early mortality after pneumonectomy for thoracic malignancies. Methods: We retrospectively analyzed all patients who underwent pneumonectomy for thoracic malignancies at our institution between 2014 and 2022. Complications were assessed up to 30 days after the operation. Mortality for any reason was recorded after 30 days and 90 days. Results: A total of 145 out of 169 patients undergoing pneumonectomy were included in this study. The postoperative 30-day complication rate was 41.4%. The 30-day-mortality was 8.3%, and 90-day-mortality 17.2%. The presence of cardiovascular comorbidities was a risk factor for major cardiopulmonary complications (54.2% vs. 13.2%, p < 0.01). Postoperative bronchus stump insufficiency (OR: 11.883, 95% CI: 1.288–109.591, p = 0.029) and American Society of Anesthesiologists (ASA) score 4 (OR: 3.023, 95% CI: 1.028–8.892, p = 0.044) were independent factors for early mortality. Conclusion: Pneumonectomy for thoracic malignancies remains a high-risk major lung resection with significant postoperative morbidity and mortality. Attention should be paid to the preoperative selection of patients. Full article
(This article belongs to the Special Issue The Current Status of Lung Cancer Surgery)
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