Exosomes and Extracellular Vesicles in Neuroprotection

Dear Colleagues, 

In the complex intercellular communication system, exosomes are a class of vesicles secreted from cells to the extracellular compartment, and their biogenesis mainly involves two invaginations of the cytoplasmic membrane, the formation of multiple vesicles, and the release of exosomes. Under normal or pathological conditions, exosomes are involved in the regulation of various signaling pathways through the delivery of various signaling molecules and play a role in the exchange of information between cells, which in turn affect the activity of recipient cells. 

In recent years, exosomes and extracellular vesicles have become biomarkers in the diagnosis and prognosis of different diseases, but also macromolecule delivery carriers for the treatment of various pathologies.

Therefore, exosomes can also be a target in the diagnosis as well as treatment of neurology-related diseases. The characterization of exosomes in the nervous system and the study of molecular mechanisms can help to deepen the understanding of exosomes in the nervous system and provide new clues for disease prevention and treatment. 

In this emerging and critical field, we invite experts to share their valuable insights, new data, or comprehensive systematic reviews.

You may choose our Joint Special Issue in IJMS.

Dr. Brian Sims
Guest Editor

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