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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Emerging Trends for Genome-Wide Association Studies in Complex Disease Genetics

edited by

Xiaowei Wu

submission deadline 20 Sep 2026 | 4 articles | Viewed by 6343 | Submission Open

Keywords: GWAS; polygenic risk scores; rare variants; structural variants; multi-omics; Mendelian randomization; population structure and relatedness; machine learning; Bayesian models; stochastic models

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Precision Molecular Oncology: From Tumor Biomarker Discovery to Next-Generation Drug Delivery

edited by

Farhadul Islam

submission deadline 20 Sep 2026 | 4 articles | Viewed by 5021 | Submission Open

Keywords: precision oncology; molecular pathology; personalized treatment; tumor marker; biomarkers; multi-omics; drug discovery; nanocarriers; drug delivery; clinical management

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms Driving Cancer Progression and Metastasis

edited by

Karolina Bajdak-Rusinek

submission deadline 20 Sep 2026 | 2 articles | Viewed by 3259 | Submission Open

Keywords: cancer progression; metastasis; epithelial–mesenchymal transition (EMT); tumor plasticity; tumor microenvironment; signaling pathways; therapy resistance

(This special issue belongs to the Section Molecular Medicine)

Molecular Biology and Functional Roles of Tumor Suppressor Genes in Cancer

edited by

Yun Zhang

submission deadline 20 Sep 2026 | 2 articles | Viewed by 1262 | Submission Open

Keywords: tumor suppressor genes; cancer biology; TP53; RB1; PTEN; genomic instability; tumor microenvironment; cancer therapy; epigenetic regulation; cell signaling

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Research in Bioactivity of Natural Products, 3rd Edition

edited by

Magdalena Bartnik

and

Wirginia Kukula-Koch

submission deadline 30 Sep 2026 | 5 articles | Viewed by 11331 | Submission Open

Keywords: molecular research; molecular properties; metabolic pathway; phytochemicals; natural products; apoptosis; bioactivity assessment; chemical composition; therapeutic targets

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Effects of Nanoparticles on Living Organisms, 3rd Edition

edited by

Yoshitaka Miyamoto

submission deadline 30 Sep 2026 | 4 articles | Viewed by 9783 | Submission Open

Keywords: nanoparticles; particulate matter; medicine; prevention; diagnosis; drug delivery; environment; nanoparticles functionalization; in vitro/in vivo evaluation; 3D model; ADME; toxicity; biomedical applications; respiratory and cardiovascular diseases; immunological, inflammatory, and allergic diseases

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Neural Networks in Molecular and Cellular Neurobiology

edited by

Paschalis Theotokis

submission deadline 30 Sep 2026 | 3 articles | Viewed by 7671 | Submission Open

Keywords: neural networks; neuroplasticity; intracellular signaling; computational neuroscience; artificial intelligence; neuromorphic computing

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Plant Hormones, Development, and Stress Tolerance

edited by

Zhaohui Chu

and

Wei Yang

submission deadline 30 Sep 2026 | 5 articles | Viewed by 6269 | Submission Open

Keywords: plant hormones; abiotic stress; auxins; jasmonic acid; signal pathway

(This special issue belongs to the Section Molecular Plant Sciences)

Latest Review Papers in Molecular Plant Science 2026

edited by

Zhaohui Chu

submission deadline 30 Sep 2026 | 3 articles | Viewed by 5700 | Submission Open

Keywords: multi-omics; plant bioreactor; plant genomics; plant-pathogens interaction; crop domestication; crop yield traits

(This special issue belongs to the Section Molecular Plant Sciences)

Current Advances in Oxytocin Research, 2nd Edition

edited by

Claudia Camerino

submission deadline 30 Sep 2026 | 1 articles | Viewed by 3207 | Submission Open

Keywords: oxytocin; thermoregulation; skeletal muscle; obesity; Prader–Willi syndrome

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Advances in Pharmacotherapeutic Strategies to Prevent Tumor Development, Progression and Treatment Resistance, 3rd Edition

edited by

Peter C. Hart

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2776 | Submission Open

Keywords: cancer; therapeutic resistance; drug tolerance; mechanisms of tumor development; mechanisms of tumor progression

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Research on Growth Hormones and Related Hormones and Peptides

edited by Hugo Alberto Barrera-Saldaña

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2645 | Submission Open

Keywords: growth hormones; insulin-like growth factor; prolactin; vasoinhibin; antiangiogenic

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Advances in Molecular Plant Physiology and Genomic Breeding of Cereals

edited by

Abdullah Shalmani

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2069 | Submission Open

Keywords: cereals; molecular physiology; genomic breeding; stress tolerance; functional genomics; genome editing; QTL mapping; multiomics; genotype–environment interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Stem Cell-Derived Cells and Bioengineering: Molecular Bases in Regeneration and Disease Research

edited by Aylin Acun

submission deadline 30 Sep 2026 | 3 articles | Viewed by 2007 | Submission Open

Keywords: stem cells; regenerative medicine; bioengineering; disease modeling; organoids; tissue engineering; decellularization; bioprinting

(This special issue belongs to the Section Molecular Medicine)

Recent Advances in Energy Metabolism

edited by

Alexander Panov

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2001 | Submission Open

Keywords: energy metabolism; glycolysis; lactate cycle; metabolic flexibility; mitochondria; respirasome; structure-function relations

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Advancements in Mass Spectrometry-Based Lipidomics for Molecular Biology Research

edited by Hua Tian

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1674 | Submission Open

Keywords: lipidomics; high resolution; spatial omics; single cell

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Mechanisms Underlying Fatty Liver Disease: From Pathogenesis to Treatment, 3rd Edition

edited by Haibo Dong and

Wei Guo

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1461 | Submission Open

Keywords: non-alcoholic fatty liver disease (NAFLD); alcohol-associated liver disease (ALD); lipotoxicity; bile acid metabolism; novel biomarker identification; organelle dysfunction and communication; inflammation and oxidative stress; cell signaling and cell death pathways; lipid metabolism and dysregulation; epigenetic modifications (DNA/RNA/non-coding RNA); therapeutic targets and interventions

(This special issue belongs to the Section Molecular Medicine)

Natural Compounds: An Adjuvant Strategy in Cancer Management, 2nd Edition

edited by Monia Cecati and

Arianna Vignini

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1025 | Submission Open

Keywords: cancer; phytochemicals; bioactive compounds; anti-tumor; cancer treatment

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Cellular and Molecular Mechanisms of Epilepsy

edited by Joaquin N. Lugo

submission deadline 30 Sep 2026 | 1 articles | Viewed by 845 | Submission Open

Keywords: pathophysiology; molecular mechanism; circuit; ion channels; comorbidities

(This special issue belongs to the Section Molecular Medicine)

Molecular Innovations in Drug Repositioning for Cancer Therapy

edited by

Ewa Trybus

and

Wojciech Trybus

submission deadline 30 Sep 2026 | 1 articles | Viewed by 476 | Submission Open

Keywords: drug repositioning; cancer therapy; therapeutic target identification; signaling pathways; drug development

(This special issue belongs to the Section Molecular Medicine)

Innovative Models for SARS-CoV-2 Pathogenesis

edited by

Virginia Lotti

submission deadline 30 Sep 2026 | 1 articles | Viewed by 475 | Submission Open

Keywords: SARS-CoV-2; coronavirus; virus infection; pathogenesis; innovative models

(This special issue belongs to the Section Molecular Medicine)

Neurochemical and Biochemical Mechanisms of Depressive Disorders

edited by

Ana B. Ramos-Hryb

and Mauricio Peña Cunha

submission deadline 30 Sep 2026 | Viewed by 268 | Submission Open

Keywords: neurochemical signaling; molecular psychiatry; biochemical biomarkers; synaptic plasticity; neuroinflammation; oxidative stress; glutamatergic system; proteomics and metabolomics; signal transduction; neuroendocrine

(This special issue belongs to the Section Molecular Medicine)

Gene Regulation and Molecular Mechanisms Underlying Plant Responses to Abiotic Stresses

edited by Talles de Oliveira Santos and

Vitor Batista Pinto

submission deadline 30 Sep 2026 | Viewed by 201 | Submission Open

Keywords: abiotic stress tolerance; gene regulation; transcription factors; epigenetic regulation; signal transduction pathways; redox homeostasis; heavy metal toxicity; nutrient imbalance; multi-omics integration; molecular plant physiology

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms and Therapeutic Advances in Hypertension Management and Vascular Health

edited by

Federica Fogacci

Arrigo Francesco Giuseppe Cicero

and

Claudio Borghi

submission deadline 20 Oct 2026 | 3 articles | Viewed by 7994 | Submission Open

Keywords: hypertension; vascular aging; endothelial dysfunction; gestational hypertension; metabolic disorders; therapeutic strategies in hypertension management

(This special issue belongs to the Section Molecular Medicine)

The Role of Bioactives in Inflammation, 2nd Edition

edited by

Chan-Yen Kuo

submission deadline 31 Oct 2026 | 13 articles | Viewed by 20456 | Submission Open

Keywords: anti-inflammation; bioactives; drug research and development; inflammatory diseases; natural products; signaling; synthesized compounds

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Therapeutic Effects of Natural Bioactive Compounds in the Management of Human Diseases: 2nd Edition

edited by

Rossana Morabito

and

Sara Spinelli

submission deadline 31 Oct 2026 | 9 articles | Viewed by 11270 | Submission Open

Keywords: natural bioactive compound; human health; chronic diseases; molecular target; oxidative stress; inflammation; cancer; diabetes

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Advances in Multi-Omics for Functional Genomics Studies and Molecular Breeding, 2nd Edition

edited by Chen Chen

submission deadline 31 Oct 2026 | 10 articles | Viewed by 9400 | Submission Open

Keywords: sequencing technologies; plant genomics; transcriptomics; proteomics; metabolomics; epigenomics; single-cell sequencing; functional genomics; transformation methods; gene identification

(This special issue belongs to the Section Molecular Plant Sciences)

Molecules at Play in Cardiovascular Diseases

edited by

Dumitru Iacobas

submission deadline 31 Oct 2026 | 7 articles | Viewed by 8889 | Submission Open

Keywords: arrythmias; arteriosclerosis; congenital heart disease; coronary disease; diabetic cardiomyopathy; dilated cardiomyopathy; endocarditis; high blood pressure; hypertrophic cardiomyopathy; valvular heart diseases

(This special issue belongs to the Section Molecular Medicine)

Advances in Drug Delivery: Molecular Mechanisms, Therapeutic Applications, and Technologies

edited by

Wenhao Wang

and

Zhengwei Huang

submission deadline 31 Oct 2026 | 4 articles | Viewed by 5720 | Submission Open

Keywords: drug delivery; stimulus-responsive drug delivery systems; controlled-release drug delivery systems; theranostics; carrier–biological system interactions; delivery barriers; molecular mechanisms

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Research on Free Radicals and Oxidative Stress—2nd Edition

edited by

Mosharraf Sarker

submission deadline 31 Oct 2026 | 5 articles | Viewed by 5275 | Submission Open

Keywords: oxidative stress; free radicals; reactive oxygen species (ROS); gene regulation; antioxidants; mitochondrial dysfunction; insulin resistance; inflammation; autophagy

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Hyperlipidemia and Molecular Mechanism in Human and Animals

edited by

Kyuhyung Choi

submission deadline 31 Oct 2026 | 1 articles | Viewed by 4462 | Submission Open

Keywords: hyperlipidemia; diabetes mellitus; Cushing’s disease; pancreatitis; gall bladder mucoceles

(This special issue belongs to the Section Molecular Medicine)

Bioinformatics in Human Disease Network Analysis

edited by

Li Liao

submission deadline 31 Oct 2026 | 5 articles | Viewed by 3890 | Submission Open

Keywords: human interactome; comorbidity; disease network; disease interaction; genotype; gene–gene interaction; graph analysis

(This special issue belongs to the Section Bioinformatics and Systems Biology)

The Contribution and Application of Molecular Biology in the Applied Biosciences—Focusing on Medicine, Biomaterials and Tissue Engineering Fields, 3rd Edition

edited by

Ioannis Tsamesidis

and

Evangelia Stalika

submission deadline 31 Oct 2026 | 6 articles | Viewed by 2844 | Submission Open

Keywords: medicine; biomaterials; tissue engineering; molecular biology; patients’ reported outcomes; personalized medicine

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Functional Genomics and Comparative Genomics Analysis in Plants, 4th Edition

edited by

Quan Zou

, Ran Su and Qiangguo Jin

submission deadline 31 Oct 2026 | 5 articles | Viewed by 2709 | Submission Open

Keywords: de novo genome sequencing; pan-genomic analyses; genome re-sequencing; GWAS analyses; RNA-seq; metabolomics; gene family analyses; plant evolutionary analyses; bioinformatics; database

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research on Metabolic Disease

edited by

Jianan Zhao

submission deadline 31 Oct 2026 | 7 articles | Viewed by 2554 | Submission Open

Keywords: metabolic diseases; diabetes mellitus; insulin resistance; glucose metabolism; lipid metabolism; diabetic complications; cardiovascular disease; molecular mechanisms; gene expression; therapeutic targets

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms of Radiation-Induced Cellular Responses

edited by

Amparo Olivares

and

Miguel Alcaraz Baños

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2000 | Submission Open

Keywords: ionizing radiation; oxidative stress; radioprotectors; radiosensitizers; antioxidant defenses; cancer therapy

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Epigenetics and Chromatin Remodeling in Cancer

edited by

Gianluca Tedaldi

and

Alessandra Virga

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1881 | Submission Open

Keywords: epigenetics; chromatin remodeling; DNA methylation; histone modifications; non-coding RNAs; circulating tumor DNA; liquid biopsy; epigenetic therapy

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms of Natural Products and Their Antioxidant Roles in Health and Disease

edited by

Kawtar Fikri-Benbrahim

and

Naoufal El Hachlafi

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1298 | Submission Open

Keywords: natural products; antioxidants; oxidative stress; molecular mechanisms; bioactive metabolites; essential oils; phytochemistry; chronic diseases; signal transduction; therapeutic applications

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Molecular Mechanisms and Therapeutic Targets in Epilepsy

edited by Daniel Rodrigo Marinowic and William Alves Martins

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1124 | Submission Open

Keywords: epilepsy; molecular mechanisms; synaptic plasticity; neuroinflammation; glial cells; pharmacoresistance; therapeutic targets; precision medicine; targeted therapy; neuroimmunology

(This special issue belongs to the Section Molecular Medicine)

Multiomics of Cancer Research in Human and Animals

edited by

Kyuhyung Choi

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1082 | Submission Open

Keywords: multiomics; cancer; epigenomics; proteomics; metabolomics

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Scoliosis and Spinal Disorders: Molecular Biomarkers and Therapeutic Strategies

edited by

Angelos Kaspiris

submission deadline 31 Oct 2026 | 1 articles | Viewed by 870 | Submission Open

Keywords: intracellular interactions during the progression of spinal disorders; molecular signaling in scoliosis; growth factor expression in spinal disorders and deformities; biomarkers; molecular-driven treatment

(This special issue belongs to the Section Molecular Medicine)

Early Molecular Diagnosis and Comprehensive Treatment of Tumors, 2nd Edition

edited by

Chan-Yen Kuo

submission deadline 31 Oct 2026 | 2 articles | Viewed by 802 | Submission Open

Keywords: next-generation sequencing (NGS); novel biomarkers; precision medicine; targeted therapy; immunotherapy; integrative treatment; personalized cancer treatment

(This special issue belongs to the Section Molecular Medicine)

Genetics and Genomics Research of Autism Spectrum Disorders

edited by

Golder N. Wilson

submission deadline 31 Oct 2026 | 1 articles | Viewed by 721 | Submission Open

Keywords: autism; neurodevelopmental disorders; genomics; copy number variants; next-generation sequencing

(This special issue belongs to the Section Molecular Medicine)

Cutting-Edge Microscopy and Electron Microscopy Innovations in Molecular Biology Research

edited by

Diana Torge

submission deadline 31 Oct 2026 | Viewed by 640 | Submission Open

Keywords: morphology; microscopy; transmission electron microscopy; molecular biology; medicine; dentistry

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Detection and Characterization of Emerging Zoonotic Diseases

edited by

Xueyong Zhang

and

Xiaofei Shang

submission deadline 31 Oct 2026 | 2 articles | Viewed by 541 | Submission Open

Keywords: emerging zoonotic diseases; molecular detection; epidemiology; pathogen ecology; molecular biology; pathogen–host interaction; detection methodology; fundamental etiology

(This special issue belongs to the Section Molecular Microbiology)

Natural Products to Pharmaceutical Agents: Molecular Mechanisms and Therapeutic Applications

edited by

Lele Yang

submission deadline 31 Oct 2026 | Viewed by 326 | Submission Open

Keywords: molecular biology; type 2 diabetes mellitus; natural products; drug discovery; therapeutic applications

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Recent Advances in Virus–Host Interactions: A Molecular Perspective

edited by

Moises Leon-Juarez

submission deadline 31 Oct 2026 | Viewed by 283 | Submission Open

Keywords: virus–host interactions; innate immunity; immune evasion; host factor; viral pathogenesis; omics technologies; antiviral targeting

(This special issue belongs to the Section Molecular Microbiology)

Gynecological Cancers: From Molecular Biology to Therapeutic Advances

edited by Leticia Rangel

submission deadline 31 Oct 2026 | Viewed by 214 | Submission Open

Keywords: gynecological oncology; molecular biology; targeted therapy; Immunotherapy; chemoresistance; signaling pathways; cancer chemotherapy; therapeutic advances; cancer genetics and epigenetics; molecular biomarkers

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms Governing Macrophage Function in Human Diseases

edited by Da Mi Kim and Wanbao Yang

submission deadline 31 Oct 2026 | Viewed by 213 | Submission Open

Keywords: macrophage biology; molecular mechanisms of macrophage; immunometabolism; metabolic reprogramming of macrophages; cell–cell interaction; microbiome–macrophage interactions; cancer-associated macrophages; metabolic disorders; neuroinflammation; macrophage-targeted therapies

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Mechanisms and Reparative Therapeutic Strategies in Neurodegenerative Diseases

edited by