Molecular Genetics of Eye Development and Myopia
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Nuclei: Function, Transport and Receptors".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 151
Special Issue Editors
Interests: high myopia; myopia; keratoconus; genetics; epigenetics; transcriptomics; candidate genes; sequence variants
Interests: extracellular matrix; corneal development and wound healing; limbal stem cells; stem cell therapy; corneal regeneration; dry eye disease; meibomian gland dysfunction
Special Issues, Collections and Topics in MDPI journals
Interests: diabetic cornea; limbal stem cells; microRNA; extracellular vesicles/exosomes; wound healing; gene therapy; stem cell therapy; corneal epithelial regeneration; intercellular communication
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Myopia (nearsightedness) is a refractive error of ≤ -0.50 dioptres [D] in which rays of light entering the eye are focused in front of the retina when ocular accommodation is relaxed. This is usually caused by the axial elongation of the eyeball; however, it can also be caused by an overly curved cornea and/or a lens with increased optical power. High myopia is a more severe form with a refractive error of ≤ -6.0 D that can lead to ocular complications in the posterior segment of the eye, including myopic maculopathy, myopic macular degeneration, posterior staphyloma, and optic neuropathy, which can ultimately culminate in blindness.
Myopia, including high myopia, is a multifactorial disorder caused by a complex interplay between environmental and genetic factors. So far, a number of myopia loci, candidate genes and sequence variants have been associated with myopia. The purpose of this Special Issue is to summarize current knowledge and highlight innovative findings regarding myopia development, thus identifying the molecular mechanisms underlying its pathogenesis and enhancing our understanding of this disorder.
We welcome the submission of original research and review articles corresponding to the molecular and cellular events responsible for myopia development.
Dr. Joanna Swierkowska
Dr. Vivien Coulson-Thomas
Dr. Mehrnoosh Saghizadeh Ghiam
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- myopia
- high myopia
- refractive error
- genetics of eye disorders
- candidate genes
- animal models
- epigenetics
- transcriptomics
- retina
- cell lines
