Cellular Mechanism of Granuloma Formation in Sarcoidosis
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: closed (30 June 2022)
Special Issue Editors
Interests: sarcoidosis; interstitial lung diseases; idiopathic pulmonary fibrosis
Special Issues, Collections and Topics in MDPI journals
Interests: pulmonary pathology; respiratory histophysiology; sarcoidosis; granuloma; comparative physiology; interstitial lung diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The special issue of Cells will be focused on the "Cellular Mechanism of Granuloma Formation in Sarcoidosis". Granulomas are a very special 3 D organization of macrophages derived immune cells associated with more or less lymphocytes resulting from both innate and adaptative immunity. They are the hallmark of so called granulomatous diseases, not only sarcoidosis, a disease with still unknown causes, but also associated with various causes as metal (Beryllium) or mycobacteria ( TB or tuberculoid leprosy). In this issue we would like to:
- highlight the similarities and differences in the constituting cells behavior in sarcoidosis granulomas versus other granulomatous diseases,
- emphazise the role of less studied cells in sarcoidosis as B lymphocytes and dendritic cells as well as epithelial and mesenchymal cells close to granulomas
- propose a model of 4 D ( in time and space ) constitution and evolution of sarcoidosis/tuberculoid granulomas
- discuss the potentail role of granulomas in the severity and evolution of sarcoidosis
- insist on the cell biology steps which could be relevant for targeted therapy
Guest Editor
Prof. Dominique Valeyre
Dr. Pr. Jean-François Bernaudin
Guest Editors
Manuscript Submission Information
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