Special Issue "Enzymatic Cascade Reactions"

A special issue of Catalysts (ISSN 2073-4344).

Deadline for manuscript submissions: 15 December 2017

Special Issue Editor

Guest Editor
Prof. Dr. Wolfgang Kroutil

Institute of Chemistry, University of Graz, NAWI Graz, BioTechMed Graz, Heinrichstrasse 28, A-8010 Graz, Austria
Website | E-Mail
Interests: enzymatic/biocatalytic methods for (asymmetric) organic synthesis

Special Issue Information

Dear Colleagues,

Cascades involving enzymes have recently become a thoroughly-investigated field. Reasons might be manifold, such as (i) the possibility of combining different types of reactions, which could not be combined in classical chemistry, (ii) the chance to prepare unstable or toxic intermediates, which are directly consumed in a subsequent step, or (iii) the option to shift the equilibrium of a reaction by removing the co(product), or (iv) simply circumventing tedious work-up of intermediates, thereby saving on reagents, solvents, time, and money. Furthermore, connecting cascades to metabolism allows to exploit metabolic intermediates or to funnel them to new products. Additionally, the elegance of creating new efficient tools for synthesis might be a driving force.

The topic encompasses cascades involving exclusively enzymes, as well as cascades combining enzymes with metal- or organocatalysis. The enzymes may be used, for instance, as isolated enzymes, as crude cell-free extract, as immobilized enzyme, or as (living) microbial cells (metabolic engineering). Here, we define a cascade as the combination of at least two chemical steps in a single reaction system without isolation of the intermediate(s). Therefore, the topic includes cascades where all steps are performed simultaneously in one pot, as well as cascades where the reaction steps are performed in a sequential manner, but still in one pot. Furthermore, cascades in flow are also of special interest.

The aim of this Special Issue is to cover promising, recent research, and novel trends in the fields of enzymatic/biocatalytic cascades, performed simultaneously (including metabolic engineering), in a sequential mode or in flow.

Prof. Dr. Wolfgang Kroutil
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Catalysts is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

This special issue is now open for submission.

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