Biosensors and Systems for Stem-Cells Electrostimulation

Dear Colleagues,

The development of stem cell-related technologies represent today a hot topic for research and companies involved in tissue engineering and regenerative medicine. New potential therapies and research areas can be promoted from the ability of optimum stem cells differentiation processes. Actual new sensing/actuation technologies based on biomaterials, electronic devices, microfluidic systems and micro-electro-mechanical systems (MEMs) open up new biomedical opportunities to measure and actuate “better”, with “alternative” methods to explore and find the insight information pursuit for physician and biologist teams, for diagnosis, therapy, clinical tests and bio-signal monitoring.  The accomplishment of new medical techniques for specific assays and tests in the health field provides significant challenges in the biomaterials, microfluidic, electronic circuits and systems required, whose performance is vital for proper and accurate lab tasks. This Special Issue is devoted principally to incorporating new proposals for stem cell development technologies, mainly based on electrostimulation signals based on new circuits and systems approaches, and its actuation effect for optimization cell differentiation.

In general, it is focused on the new electrostimulation setups, electrode layout design and biomaterial selection involved, bio-signal analog front-end (AFE) circuits; specific circuits development for known and new sensor/sensing approaches; circuits for biomedical signal processing; devices; circuits and systems for clinical applications; circuits for sensing/actuation in MEM systems, lab-on-a-chip (LoC), micro-total-analysis systems (uTAS); cell assays and manipulation, etc. Tissue engineering and regenerative medicine. The main topics of interest include, but are not limited to:

• Electrostimulation techniques (AC/DC) and circuits
• Design, manufacture and characterization of new biomaterials
• 2D and 3D electrode design
• Stem cell culture
• Differentiation
• Analog Front-End (AFE) circuits
• Cells, stem cells and tissue electrical models
• Bioimpedance and capacitive based circuits
• Circuits for new sensing/monitoring devices and microelectrodes
• Circuits, systems and MEMs in stem cell clinical applications
• Tissue engineering applications: N2A, myoblast, osteoblast and others
• Other biosensors: chemical, optical, mechanical

Dr. Alberto Yufera
Prof. Dr. Yadir Torres Hernández
Guest Editors

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