Cellular Biology of Brain Angiogenesis
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cell Biology".
Deadline for manuscript submissions: closed (2 February 2024) | Viewed by 237
Special Issue Editors
Interests: angiogenesis; neurovascular unit; blood-brain barrier; cerebrovascular disease; small vessel malformations; inherited retinal dystrophies; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Interests: molecular genetics and predictive medicine; molecular biology; genetics; DNA sequencing; population genetics; SNPs; genetic and molecular mechanisms involved in the pathogenesis of cerebrovascular diseases; cerebral cavernous malformations; identification of candidate genes and causative variants in different forms of retinitis pigmentosa; molecular genetic features and genotype–phenotype correlations in trimethylaminuria
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
At the embryo stage, the development of brain vasculature includes three different phases: vasculogenesis, angiogenesis and arterial specialization. Specific molecular events selectively drive each phase. Several growth factors and neurotropic molecules secreted by endothelial, glial and nervous cells act in a paracrine manner, leading to the correct neurovascular development. However, vascular remodeling also continues during adulthood. The perturbation of pathways controlling brain vascular homeostasis results in aberrant vessel morphogenesis and congenital vascular malformation development. This Special Issue aims to collect research articles, reviews and communications focusing on mechanisms related to brain angiogenesis in both physiological and pathological conditions, as well as those related to oxidative damage. Moreover, submission of manuscripts describing the regulation of blood–brain barrier permeability and the cross-talk at the neurovascular unit is also encouraged. In this context, reports of single-cell transcriptomics, ATAC and methylome analysis can be considered for publication. Studies performed on human samples, cell lines and animal models can be considered.
Dr. Concetta Scimone
Dr. Rosalia D’Angelo
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- brain angiogenesis
- vasculogenesis
- arterialization
- neurovascular unit
- blood–brain barrier
- endothelial permeability
- oxidative damage
