Staphylococcal Biology and Pathogenesis
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: 31 December 2024 | Viewed by 782
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Special Issue will focus upon the recent advances in staphylococcal biology, aiming to elucidate its complex mechanisms of pathogenesis. New data on cell wall and surface structures (teichoic acids, lipids, protein A, TcaA, polysaccharide intercellular adhesin) and extra-cellular enzymes (DNases, hemolysins) have demonstrated the wide array of mechanisms utilized by staphylococci to cause persistent infections. Data on how the metabolism impacts antibiotic resistance and macrophage activation (host–bacterial interactions) reveal an extremely dynamic interplay between the host and pathogen. A prophage that enhances persistent bacteremia via novel mechanisms has been identified. Finally, the complex immunological responses to S. aureus (allergic response; persistence due to IL-10; hyper-responsiveness in humanized mice; non-protective imprinting) enable a deeper understanding of the host–pathogen interactions. All of this complexity helps to clarify why the development of a staphylococcal vaccine is so challenging.
Prof. Dr. Richard Proctor
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
