Microbial Resistance to Carbapenems: Epidemiology, Detection and Treatment Options
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Mechanism and Evolution of Antibiotic Resistance".
Deadline for manuscript submissions: 30 June 2024 | Viewed by 4485
Special Issue Editors
Interests: penicillin derivative; carbapenem derivative; urinary tract infections; acinetobacter baumannii; carbapenems; colistin
Interests: antibiotic resistance mechanisms; phenotypic and molecular methods for antibiotic resistance detection; Klebsiella pneumoniae; Pseudomonas aeruginosa; Acinetobacter baumannii; SARS-CoV-2; clinical microbiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
During the last few years, we have been witnessing the adverse effects of the ‘post-antibiotic era’, characterized by ineffective drugs and the development of superbugs. Antimicrobial resistance represents a major threat to global health, and it has significant impacts regarding morbidity, mortality and healthcare costs. In particular, carbapenem resistance has emerged in Gram-negative pathogens such as Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacterales, which are often implicated in serious, difficult-to-treat health-care-associated infections. The global epidemiology of carbapenem-resistant organisms is of great interest, as acquired carbapenem resistance via carbapenemases is transferrable among Gram-negative microorganisms. Notably, carbapenem-resistant Gram-negative bacteria are under surveillance in many countries. There is also an apparent need for timely detection methods in clinical diagnostics and appropriate therapeutic approaches. Carbapenem-resistant, Gram-negative bacteria are listed by the WHO as pathogens with critical priority for the development of new drugs. Currently, a few new drugs and combinations, as well as old, revived drugs, have been used for the treatment of infections due to carbapenem-resistant pathogens. Therefore, this Special Issue seeks manuscripts regarding:
- The epidemiology of carbapenem-resistant Gram-negative bacteria;
- Different laboratory methodologies for prompt detection;
- Treatment options for infections attributed to carbapenem-resistant pathogens.
Dr. Vasiliki Koumaki
Dr. Efthymia Protonotariou
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- carbapenems
- carbapenemases
- Gram-negatives
- multidrug resistance (MDR)
- carpabenem-resistant organisms (CROs)
- antimicrobial resistance
- carbapenem resistance detection
- epidemiology
- antibiotics
- carbapenem-resistant Gram-negative bacteria (CRGNB)