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Cosmetics 2016, 3(3), 21; doi:10.3390/cosmetics3030021

Contact Allergy to Hair Dyes

Department of Dermatology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands
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Author to whom correspondence should be addressed.
Academic Editors: Emanuela Corsini and David Basketter
Received: 5 February 2016 / Revised: 20 June 2016 / Accepted: 20 June 2016 / Published: 29 June 2016
(This article belongs to the Special Issue Cosmetic Contact Allergens)
View Full-Text   |   Download PDF [187 KB, uploaded 29 June 2016]

Abstract

Many strong and extreme sensitizing chemicals, such as para-phenylenediamine (PPD), toluene-2,5-diamine (TDA) and other aromatic amines or cross-reacting substances, are ingredients in hair dye products. The chemistry of hair dyeing and the immunological reactions to the potent sensitizing hair dye components are complex and have not been fully clarified up until now. Recently 2-methoxymethyl-p-phenylenediamine (ME-PPD), a PPD derivate with moderate skin-sensitizing properties, was developed. Although developed for the prevention of sensitization, ME-PPD appears to be tolerated in some PPD/TDA-allergic individuals. View Full-Text
Keywords: contact allergy; allergic contact dermatitis; patch tests; hair dyes; p-phenylenediamine; 2,5-toluenediamine; 2-methoxymethyl-p-phenylenediamine contact allergy; allergic contact dermatitis; patch tests; hair dyes; p-phenylenediamine; 2,5-toluenediamine; 2-methoxymethyl-p-phenylenediamine
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Schuttelaar, M.-L.A.; Vogel, T.A. Contact Allergy to Hair Dyes. Cosmetics 2016, 3, 21.

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