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Nanomaterials 2016, 6(1), 5;

Biosensors Incorporating Bimetallic Nanoparticles

NanoElectrochemistry Laboratory, Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan
National Synchrotron Radiation Research Center, Hsinchu 300, Taiwan
Author to whom correspondence should be addressed.
Academic Editor: Ming Su
Received: 12 November 2015 / Revised: 11 December 2015 / Accepted: 16 December 2015 / Published: 31 December 2015
(This article belongs to the Special Issue Nanomaterials for Biosensing Applications)
View Full-Text   |   Download PDF [968 KB, uploaded 31 December 2015]   |  


This article presents a review of electrochemical bio-sensing for target analytes based on the use of electrocatalytic bimetallic nanoparticles (NPs), which can improve both the sensitivity and selectivity of biosensors. The review moves quickly from an introduction to the field of bio-sensing, to the importance of biosensors in today’s society, the nature of the electrochemical methods employed and the attendant problems encountered. The role of electrocatalysts is introduced with reference to the three generations of biosensors. The contributions made by previous workers using bimetallic constructs, grouped by target analyte, are then examined in detail; following which, the synthesis and characterization of the catalytic particles is examined prior to a summary of the current state of endeavor. Finally, some perspectives for the future of bimetallic NPs in biosensors are given. View Full-Text
Keywords: biosensor; bimetallic; nanoparticle; electrocatalytic; catalytic biosensor; bimetallic; nanoparticle; electrocatalytic; catalytic

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Rick, J.; Tsai, M.-C.; Hwang, B.J. Biosensors Incorporating Bimetallic Nanoparticles. Nanomaterials 2016, 6, 5.

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