Rafts, Nanoparticles and Neural Disease
AbstractThis review examines the role of membrane rafts in neural disease as a rationale for drug targeting utilizing lipid-based nanoparticles. The article begins with an overview of methodological issues involving the existence, sizes, and lifetimes of rafts, and then examines raft function in the etiologies of three major neural diseases—epilepsy, Parkinson’s disease, and Alzheimer’s disease—selected as promising candidates for raft-based therapeutics. Raft-targeting drug delivery systems involving liposomes and solid lipid nanoparticles are then examined in detail. View Full-Text
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Gulati, V.; Wallace, R. Rafts, Nanoparticles and Neural Disease. Nanomaterials 2012, 2, 217-250.
Gulati V, Wallace R. Rafts, Nanoparticles and Neural Disease. Nanomaterials. 2012; 2(3):217-250.Chicago/Turabian Style
Gulati, Vishal; Wallace, Ron. 2012. "Rafts, Nanoparticles and Neural Disease." Nanomaterials 2, no. 3: 217-250.