Next Article in Journal
Influence of High Shear Dispersion on the Production of Cellulose Nanofibers by Ultrasound-Assisted TEMPO-Oxidation of Kraft Pulp
Next Article in Special Issue
Investigation of Sub-100 nm Gold Nanoparticles for Laser-Induced Thermotherapy of Cancer
Previous Article in Journal
All-Solid-State Textile Batteries Made from Nano-Emulsion Conducting Polymer Inks for Wearable Electronics
Previous Article in Special Issue
Rafts, Nanoparticles and Neural Disease
Article Menu

Export Article

Open AccessCommunication
Nanomaterials 2012, 2(3), 275-285; doi:10.3390/nano2030275

Assembly of DNA Architectures in a Non-Aqueous Solution

RDRL-SEE-B, Adelphi, MD 20783, USA
Episensors, Inc., 590 Territorial Drive, Bolingbrook, IL 60440, USA
Author to whom correspondence should be addressed.
Received: 18 June 2012 / Revised: 8 August 2012 / Accepted: 20 August 2012 / Published: 31 August 2012
(This article belongs to the Special Issue Trends of Nanomaterials in Life Sciences)
View Full-Text   |   Download PDF [1792 KB, uploaded 31 August 2012]   |  


In the present work, the procedures for the creation of self-assembled DNA nanostructures in aqueous and non-aqueous media are described. DNA-Surfactant complex formation renders the DNA soluble in organic solvents offering an exciting way to bridge the transition of DNA origami materials electronics applications. The DNA retains its structural features, and these unique geometries provide an interesting candidate for future electronics and nanofabrication applications with potential for new properties. The DNA architectures were first assembled under aqueous conditions, and then characterized in solution (using circular dichroism (CD) spectroscopy) and on the surface (using atomic force microscopy (AFM)). Following aqueous assembly, the DNA nanostructures were transitioned to a non-aqueous environment, where butanol was chosen for optical compatibility and thermal properties. The retention of DNA hierarchical structure and thermal stability in non-aqueous conditions were confirmed via CD spectroscopy. The formation and characterization of these higher order DNA-surfactant complexes is described in this paper. View Full-Text
Keywords: DNA nanostructures; bioelectronics; biodirected assembly; CTAC; DNA DNA nanostructures; bioelectronics; biodirected assembly; CTAC; DNA

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Finch, A.S.; Anton, C.M.; Jacob, C.M.; Proctor, T.J.; Stratis-Cullum, D.N. Assembly of DNA Architectures in a Non-Aqueous Solution. Nanomaterials 2012, 2, 275-285.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Nanomaterials EISSN 2079-4991 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top