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Vaccines, Volume 4, Issue 1

2016 March - 7 articles

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Articles (7)

  • Article
  • Open Access
4 Citations
6,225 Views
11 Pages

Intranasal Vaccination Affords Localization and Persistence of Antigen-Specific CD8+ T Lymphocytes in the Female Reproductive Tract

  • Shailbala Singh,
  • Kimberly S. Schluns,
  • Guojun Yang,
  • Scott M. Anthony,
  • Michael A. Barry and
  • K. Jagannadha Sastry

Immunization strategies generating large numbers of antigen-specific T cells in the female reproductive tract (FRT) can provide barrier protection against sexually-transmitted pathogens, such as the human immunodeficiency virus (HIV) and human papill...

  • Review
  • Open Access
52 Citations
15,756 Views
17 Pages

Hepatitis Vaccines

  • Sina Ogholikhan and
  • Kathleen B. Schwarz

Viral hepatitis is a serious health problem all over the world. However, the reduction of the morbidity and mortality due to vaccinations against hepatitis A and hepatitis B has been a major component in the overall reduction in vaccine preventable d...

  • Review
  • Open Access
94 Citations
15,767 Views
20 Pages

29 February 2016

Cytokines are believed to be crucial mediators of chronic intestinal inflammation in inflammatory bowel diseases (IBD) such as Crohn’s disease (CD) and ulcerative colitis (UC). Many of these cytokines trigger cellular effects and functions through si...

  • Review
  • Open Access
27 Citations
7,317 Views
15 Pages

22 February 2016

Pneumococcal infection is one of the leading causes of death worldwide, especially in children of developing and underdeveloped countries. Capsular polysaccharide-based vaccines are available for the prevention of this disease. A 7-valent pneumococca...

  • Review
  • Open Access
23 Citations
7,762 Views
20 Pages

22 January 2016

HIV-1 virus-like particles (VLPs) are promising vaccine candidates against HIV-1 infection. They are capable of preserving the native conformation of HIV-1 antigens and priming CD4+ and CD8+ T cell responses efficiently via cross presentation by both...

  • Communication
  • Open Access
30 Citations
7,998 Views
8 Pages

Anti-IgE Qb-VLP Conjugate Vaccine Self-Adjuvants through Activation of TLR7

  • Bassel Akache,
  • Risini D. Weeratna,
  • Aparna Deora,
  • Jennifer M. Thorn,
  • Brian Champion,
  • James R. Merson,
  • Heather L. Davis and
  • Michael J. McCluskie

21 January 2016

Qb bacteriophage virus-like particles (Qb-VLP) are utilized as carriers to enhance immune responses to weakly or non-immunogenic antigens such as peptides and haptens. Qb-VLPs are formed through the self-assembly of multiple Qb capsid protein monomer...

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Vaccines - ISSN 2076-393X