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Water 2013, 5(2), 767-779; doi:10.3390/w5020767

Determination of Perchlorate in Bottled Water from Italy

Department of Chemistry and Biology, University of Salerno, via Giovanni Paolo II 132, Fisciano 84084, Italy
Department of Human, Philosophical and Educational Science, University of Salerno, via Giovanni Paolo II 132, Fisciano 84084, Italy
Author to whom correspondence should be addressed.
Received: 8 April 2013 / Revised: 28 May 2013 / Accepted: 31 May 2013 / Published: 13 June 2013
(This article belongs to the Special Issue Analytical Chemistry of Water)
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Perchlorate is regarded as an emerging persistent inorganic contaminant. It is widely known that perchlorate is an endocrine disruptor as it competitively inhibits iodide transport in the thyroid gland. As drinking water is the major source of human exposure to perchlorate, its occurrence in commercially available bottled waters purchased in different regions of Italy was investigated. Perchlorate was measured using the rapid, sensitive, and selective LC-ESI-MS/MS (liquid chromatography-electrospray tandem mass spectrometry) method by multiple reaction monitoring (MRM) of the transition 98.8→82.8, which corresponds to the loss of one oxygen atom in the perchlorate ion (ClO4→ClO3). The chlorine isotope ratio (35Cl/37Cl) was used as a confirmation tool. The limit of quantification (LOQ) for this method was 5 ng/L, and the recovery ranged from 94% to 108%. Perchlorate was detected in 44 of the 62 drinking waters tested, with concentrations ranging from <5 to 75 ng/L. These values are similar in magnitude to those reported in drinking water from the USA and do not pose an immediate health concern.
Keywords: perchlorate; drinking water; LC-ESI–MS/MS; multiple reaction monitoring (MRM) perchlorate; drinking water; LC-ESI–MS/MS; multiple reaction monitoring (MRM)
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Iannece, P.; Motta, O.; Tedesco, R.; Carotenuto, M.; Proto, A. Determination of Perchlorate in Bottled Water from Italy. Water 2013, 5, 767-779.

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