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Cancers 2010, 2(2), 549-566; doi:10.3390/cancers2020549

Management of Melanoma Families

Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands
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Received: 11 February 2010 / Revised: 12 April 2010 / Accepted: 14 April 2010 / Published: 16 April 2010
(This article belongs to the Special Issue Current Concepts in the Diagnosis and Treatment of Cutaneous Melanoma)
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Abstract

In this review we have aimed to focus on the clinical management of familial melanoma patients and their relatives. Along this line three major topics will be discussed: (1) management/screening of familial melanoma families: what is advised and what is the evidence thereof; (2) variability of families worldwide with regard to clinical phenotype, including cancer spectrum and likelihood of finding germline mutations and (3) background information for clinicians on the molecular biology of familial melanoma and recent developments in this field. View Full-Text
Keywords: familial melanoma; hereditary melanoma; FAMMM syndrome; pancreatic carcinoma; management; surveillance; screening; DNA testing; CDKN2A familial melanoma; hereditary melanoma; FAMMM syndrome; pancreatic carcinoma; management; surveillance; screening; DNA testing; CDKN2A
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Bergman, W.; Gruis, N.A. Management of Melanoma Families. Cancers 2010, 2, 549-566.

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