Cancers 2010, 2(2), 397-419; doi:10.3390/cancers2020397
Review

Current Research and Development of Chemotherapeutic Agents for Melanoma

Kyaw Minn Hsan 1,2,† email, Chun-Chieh Chen 1,2,† email and Lie-Fen Shyur 2,* email
1 Institute of Plant Biology, National Taiwan University, Taipei 106, Taiwan 2 Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan † Both authors contributed equally to this article.
* Author to whom correspondence should be addressed.
Received: 25 February 2010; in revised form: 25 March 2010 / Accepted: 6 April 2010 / Published: 9 April 2010
(This article belongs to the Special Issue Current Concepts in the Diagnosis and Treatment of Cutaneous Melanoma)
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Abstract: Cutaneous malignant melanoma is the most lethal form of skin cancer and an increasingly common disease worldwide. It remains one of the most treatment-refractory malignancies. The current treatment options for patients with metastatic melanoma are limited and in most cases non-curative. This review focuses on conventional chemotherapeutic drugs for melanoma treatment, by a single or combinational agent approach, but also summarizes some potential novel phytoagents discovered from dietary vegetables or traditional herbal medicines as alternative options or future medicine for melanoma prevention. We explore the mode of actions of these natural phytoagents against metastatic melanoma.
Keywords: cutaneous malignant melanoma; metastasis; chemotherapeutic drugs; herbal medicines; phytoagents

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Cite This Article

MDPI and ACS Style

Hsan, K.M.; Chen, C.-C.; Shyur, L.-F. Current Research and Development of Chemotherapeutic Agents for Melanoma. Cancers 2010, 2, 397-419.

AMA Style

Hsan KM, Chen C-C, Shyur L-F. Current Research and Development of Chemotherapeutic Agents for Melanoma. Cancers. 2010; 2(2):397-419.

Chicago/Turabian Style

Hsan, Kyaw Minn; Chen, Chun-Chieh; Shyur, Lie-Fen. 2010. "Current Research and Development of Chemotherapeutic Agents for Melanoma." Cancers 2, no. 2: 397-419.

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