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Cancers 2010, 2(2), 397-419; doi:10.3390/cancers2020397

Current Research and Development of Chemotherapeutic Agents for Melanoma

Institute of Plant Biology, National Taiwan University, Taipei 106, Taiwan
Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan
Both authors contributed equally to this article.
Author to whom correspondence should be addressed.
Received: 25 February 2010 / Revised: 25 March 2010 / Accepted: 6 April 2010 / Published: 9 April 2010
(This article belongs to the Special Issue Current Concepts in the Diagnosis and Treatment of Cutaneous Melanoma)
View Full-Text   |   Download PDF [227 KB, uploaded 9 April 2010]


Cutaneous malignant melanoma is the most lethal form of skin cancer and an increasingly common disease worldwide. It remains one of the most treatment-refractory malignancies. The current treatment options for patients with metastatic melanoma are limited and in most cases non-curative. This review focuses on conventional chemotherapeutic drugs for melanoma treatment, by a single or combinational agent approach, but also summarizes some potential novel phytoagents discovered from dietary vegetables or traditional herbal medicines as alternative options or future medicine for melanoma prevention. We explore the mode of actions of these natural phytoagents against metastatic melanoma. View Full-Text
Keywords: cutaneous malignant melanoma; metastasis; chemotherapeutic drugs; herbal medicines; phytoagents cutaneous malignant melanoma; metastasis; chemotherapeutic drugs; herbal medicines; phytoagents
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Hsan, K.M.; Chen, C.-C.; Shyur, L.-F. Current Research and Development of Chemotherapeutic Agents for Melanoma. Cancers 2010, 2, 397-419.

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