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Micromachines 2016, 7(9), 170;

Deformability-Based Electrokinetic Particle Separation

Mechanical and Electrical Engineering College, Hainan University, Haikou 570228, China
School of Mechanical Engineering, Yeungnam University, Gyongsan 712-719, Korea
Department of Chemical and Materials Engineering, National Yunlin University of Science and Technology, Yunlin 64002, Taiwan
School of Energy Science and Engineering, Harbin Institute of Technology, Harbin 150001, China
Laboratoire JA Dieudonné, UMR CNRS 7351, Université Côte d’Azur, Université de Nice Sophia Antipolis, Parc Valrose 06108 Nice Cedex 02, France
Author to whom correspondence should be addressed.
Academic Editors: Xiangchun Xuan and Shizhi Qian
Received: 14 July 2016 / Revised: 5 September 2016 / Accepted: 7 September 2016 / Published: 20 September 2016
(This article belongs to the Special Issue Micro/Nano-Chip Electrokinetics)
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Deformability is an effective property that can be used in the separation of colloidal particles and cells. In this study, a microfluidic device is proposed and tested numerically for the sorting of deformable particles of various degrees. The separation process is numerically investigated by a direct numerical simulation of the fluid–particle–electric field interactions with an arbitrary Lagrangian–Eulerian finite-element method. The separation performance is investigated with the shear modulus of particles, the strength of the applied electric field, and the design of the contracted microfluidic devices as the main parameters. The results show that the particles with different shear moduli take different shapes and trajectories when passing through a microchannel contraction, enabling the separation of particles based on their difference in deformability. View Full-Text
Keywords: arbitrary Lagrangian–Eulerian (ALE); dielectrophoresis; microfluidic; particle separation arbitrary Lagrangian–Eulerian (ALE); dielectrophoresis; microfluidic; particle separation

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Zhou, T.; Yeh, L.-H.; Li, F.-C.; Mauroy, B.; Joo, S.W. Deformability-Based Electrokinetic Particle Separation. Micromachines 2016, 7, 170.

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