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Micromachines 2016, 7(11), 195; doi:10.3390/mi7110195

Tunable Particle Focusing in a Straight Channel with Symmetric Semicircle Obstacle Arrays Using Electrophoresis-Modified Inertial Effects

1
School of Mechanical, Materials and Mechatronic Engineering, University of Wollongong, Wollongong, NSW 2522, Australia
2
School of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China
*
Author to whom correspondence should be addressed.
Academic Editors: Xiangchun Xuan and Shizhi Qian
Received: 23 September 2016 / Revised: 13 October 2016 / Accepted: 19 October 2016 / Published: 1 November 2016
(This article belongs to the Special Issue Micro/Nano-Chip Electrokinetics)
View Full-Text   |   Download PDF [3425 KB, uploaded 1 November 2016]   |  

Abstract

In this work, a novel microfluidic platform for tunable particle focusing in a straight channel with symmetric semicircle obstacle arrays using electrophoresis (EP)-modified inertial effects was presented. By exerting an EP force on the charged microparticles, a relative velocity gap between microspheres and fluid in a straight channel with symmetric semicircle obstacle arrays was implemented. The relative velocity and fluid shear will induce shear-slip lift force (Saffman lift force) perpendicular to the mainstream direction. Therefore, the focusing pattern can be altered using the electrophoresis-induced Saffman force. The effects of electric field direction, flow rate, electric field magnitude, and particle size were also studied. This demonstrates the possibility of adjusting the particle inertial focusing pattern in a straight channel with with symmetric semicircle obstacle arrays using electrophoresis. Manipulation of the lateral migration of focusing streaks increases controllability in applications such as blood cell filtration and the separation of cells by size. View Full-Text
Keywords: particle focusing; electrophoresis force; Saffman lift force particle focusing; electrophoresis force; Saffman lift force
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Yuan, D.; Pan, C.; Zhang, J.; Yan, S.; Zhao, Q.; Alici, G.; Li, W. Tunable Particle Focusing in a Straight Channel with Symmetric Semicircle Obstacle Arrays Using Electrophoresis-Modified Inertial Effects. Micromachines 2016, 7, 195.

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