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Micromachines 2016, 7(8), 136; doi:10.3390/mi7080136

A Reduced Graphene Oxide Based Radio Frequency Glucose Sensing Device Using Multi-Dimensional Parameters

School of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-749, Korea
Department of Computer Engineering, Gachon University, Gyeonggi-do 461-701, Korea
Author to whom correspondence should be addressed.
Academic Editor: Hiroshi Mizuta
Received: 30 May 2016 / Revised: 19 July 2016 / Accepted: 1 August 2016 / Published: 5 August 2016
(This article belongs to the Special Issue Graphene Nano-Electro-Mechanical (NEM) Devices and Applications)
View Full-Text   |   Download PDF [2272 KB, uploaded 5 August 2016]   |  


A reduced graphene oxide (RGO) based glucose sensor using a radio frequency (RF) signal is demonstrated. An RGO with outstanding electrical property was employed as the interconnector material between signal electrodes in an RF electric circuit, and it was functionalized with phenylbutyric acid (PBA) as a linker molecule to bind glucoses. By adding glucose solution, the fabricated sensor with RGO and PBA showed detecting characteristics in RF signal transmission and reflection. Frequency dependent electrical parameters such as resistance, inductance, shunt conductance and shunt capacitance were extracted from the RF results under the equivalent circuit model. These parameters also provided sensing characteristics of glucose with different concentrations. Using these multi-dimensional parameters, the RF sensor device detected glucose levels in the range of 1–4 mM, which ordinarily covers the testing range for diabetes or medical examination. The RGO based RF sensor, which fits well to a linear curve with fine stability, holds considerable promise for biomaterials detection, including glucose. View Full-Text
Keywords: glucose biosensor; multi-dimensional parameters; radio frequency; reduced graphene oxide glucose biosensor; multi-dimensional parameters; radio frequency; reduced graphene oxide

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Park, B.; Park, H.G.; Ji, J.-H.; Cho, J.; Jun, S.C. A Reduced Graphene Oxide Based Radio Frequency Glucose Sensing Device Using Multi-Dimensional Parameters. Micromachines 2016, 7, 136.

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