Integration of a Droplet-Based Microfluidic System and Silicon Nanoribbon FET Sensor
AbstractWe present a novel microfluidic system that integrates droplet microfluidics with a silicon nanoribbon field-effect transistor (SiNR FET), and utilize this integrated system to sense differences in pH. The device allows for selective droplet transfer to a continuous water phase, actuated by dielectrophoresis, and subsequent detection of the pH level in the retrieved droplets by SiNR FETs on an electrical sensor chip. The integrated microfluidic system demonstrates a label-free detection method for droplet microfluidics, presenting an alternative to optical fluorescence detection. In this work, we were able to differentiate between droplet trains of one pH-unit difference. The pH-based detection method in our integrated system has the potential to be utilized in the detection of biochemical reactions that induce a pH-shift in the droplets. View Full-Text
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Afrasiabi, R.; Soderberg, L.M.; Joensson, H.N.; Björk, P.; Andersson Svahn, H.; Linnros, J. Integration of a Droplet-Based Microfluidic System and Silicon Nanoribbon FET Sensor. Micromachines 2016, 7, 134.
Afrasiabi R, Soderberg LM, Joensson HN, Björk P, Andersson Svahn H, Linnros J. Integration of a Droplet-Based Microfluidic System and Silicon Nanoribbon FET Sensor. Micromachines. 2016; 7(8):134.Chicago/Turabian Style
Afrasiabi, Roodabeh; Soderberg, Lovisa M.; Joensson, Haakan N.; Björk, Per; Andersson Svahn, Helene; Linnros, Jan. 2016. "Integration of a Droplet-Based Microfluidic System and Silicon Nanoribbon FET Sensor." Micromachines 7, no. 8: 134.
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