Next Article in Journal
A Microchip for High-Throughput Axon Growth Drug Screening
Next Article in Special Issue
Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans
Previous Article in Journal / Special Issue
Light-Addressable Potentiometric Sensor as a Sensing Element in Plug-Based Microfluidic Devices
Article Menu

Export Article

Open AccessCommunication
Micromachines 2016, 7(7), 113; doi:10.3390/mi7070113

Microfluidic Autologous Serum Eye-Drops Preparation as a Potential Dry Eye Treatment

1
Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan
2
ImPACT Research Center for Advanced Nanobiodevices, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan
3
Japan Science and Technology Agency (JST), PRESTO, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan
4
Division of Applied Chemistry, Faculty of Engineering, Hokkaido University, Sapporo 060-8628, Japan
5
Department of Ophthalmology, School of Medicine, Keio University, Tokyo 160-8582, Japan
6
Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu 761-0395, Japan
*
Authors to whom correspondence should be addressed.
Academic Editors: Andrew J. deMello and Nam-Trung Nguyen
Received: 27 May 2016 / Revised: 22 June 2016 / Accepted: 30 June 2016 / Published: 4 July 2016
(This article belongs to the Special Issue Micro/Nano Devices for Chemical Analysis)
View Full-Text   |   Download PDF [2214 KB, uploaded 4 July 2016]   |  

Abstract

Dry eye is a problem in tearing quality and/or quantity and it afflicts millions of persons worldwide. An autologous serum eye-drop is a good candidate for dry eye treatment; however, the eye-drop preparation procedures take a long time and are relatively troublesome. Here we use spiral microchannels to demonstrate a strategy for the preparation of autologous serum eye-drops, which provide benefits for all dry eye patients; 100% and 90% removal efficiencies are achieved for 10 μm microbeads and whole human blood cells, respectively. Since our strategy allows researchers to integrate other functional microchannels into one device, such a microfluidic device will be able to offer a new one-step preparation system for autologous serum eye-drops. View Full-Text
Keywords: dry eye; autologous serum eye-drops; spiral microchannel dry eye; autologous serum eye-drops; spiral microchannel
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Yasui, T.; Morikawa, J.; Kaji, N.; Tokeshi, M.; Tsubota, K.; Baba, Y. Microfluidic Autologous Serum Eye-Drops Preparation as a Potential Dry Eye Treatment. Micromachines 2016, 7, 113.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Micromachines EISSN 2072-666X Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top