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Formation of Tunable, Emulsion Micro-Droplets Utilizing Flow-Focusing Channels and a Normally-Closed Micro-Valve
Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu 300, Taiwan
* Author to whom correspondence should be addressed.
Received: 13 June 2013; in revised form: 7 July 2013 / Accepted: 8 July 2013 / Published: 17 July 2013
Abstract: A mono-dispersed emulsion is of great significance in many chemical, biomedical and industrial applications. The current study reports a new microfluidic chip capable of forming tunable micro-droplets in liquids for emulsification applications. It can precisely generate size-tunable, uniform droplets using flow-focusing channels and a normally-closed valve, which is opened by a pneumatic suction force. Experimental data showed that micro-droplets with a diameter ranging from several to tens of micrometers could be precisely generated with a high uniformity. The droplet size is experimentally found to be dependent on the velocity of the dispersed-phase liquid, which is controlled by the deflection of the suction membrane. Emulsions with droplet sizes ranging from 5.5 to 55 μm are successfully observed. The variation in droplet sizes is from 3.8% to 2.5%. The micro-droplets have a uniform size and droplets smaller than those reported in previous studies are possible with this approach. This new microfluidic device can be promising for emulsification and other related applications.
Keywords: microfluidics; emulsification; normally-closed valve; suction force
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Cite This Article
MDPI and ACS Style
Wang, J.-H.; Lee, G.-B. Formation of Tunable, Emulsion Micro-Droplets Utilizing Flow-Focusing Channels and a Normally-Closed Micro-Valve. Micromachines 2013, 4, 306-320.
Wang J-H, Lee G-B. Formation of Tunable, Emulsion Micro-Droplets Utilizing Flow-Focusing Channels and a Normally-Closed Micro-Valve. Micromachines. 2013; 4(3):306-320.
Wang, Jung-Hao; Lee, Gwo-Bin. 2013. "Formation of Tunable, Emulsion Micro-Droplets Utilizing Flow-Focusing Channels and a Normally-Closed Micro-Valve." Micromachines 4, no. 3: 306-320.