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Toxins 2012, 4(2), 98-109; doi:10.3390/toxins4020098
Communication

Sorption of Ochratoxin A from Aqueous Solutions Using β-Cyclodextrin-Polyurethane Polymer

1,*  and 2
1 Bacterial Foodborne Pathogens and Mycology Research Unit, United States Department of Agriculture, Agricultural Research Service, National Center for Agricultural Utilization Research, 1815 N. University St., Peoria, IL 61604, USA 2 Renewable Product Technology Research Unit, United States Department of Agriculture, Agricultural Research Service, National Center for Agricultural Utilization Research, 1815 N. University St., Peoria, IL 61604, USA
* Author to whom correspondence should be addressed.
Received: 14 November 2011 / Revised: 14 December 2011 / Accepted: 31 January 2012 / Published: 6 February 2012
(This article belongs to the Special Issue Ochratoxins 2011-2012)
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Abstract

The ability of a cyclodextrin-polyurethane polymer to remove ochratoxin A from aqueous solutions was examined by batch rebinding assays. The results from the aqueous binding studies were fit to two parameter models to gain insight into the interaction of ochratoxin A with the nanosponge material. The ochratoxin A sorption data fit well to the heterogeneous Freundlich isotherm model. The polymer was less effective at binding ochratoxin A in high pH buffer (9.5) under conditions where ochratoxin A exists predominantly in the dianionic state. Batch rebinding assays in red wine indicate the polymer is able to remove significant levels of ochratoxin A from spiked solutions between 1–10 μg·L−1. These results suggest cyclodextrin nanosponge materials are suitable to reduce levels of ochratoxin A from spiked aqueous solutions and red wine samples.
Keywords: ochratoxin A; nanosponge; isotherm analysis; red wine; decontamination ochratoxin A; nanosponge; isotherm analysis; red wine; decontamination
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Appell, M.; Jackson, M.A. Sorption of Ochratoxin A from Aqueous Solutions Using β-Cyclodextrin-Polyurethane Polymer. Toxins 2012, 4, 98-109.

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