Toxins 2010, 2(7), 1718-1750; doi:10.3390/toxins2071718
Review

Chemical, Physical and Biological Approaches to Prevent Ochratoxin Induced Toxicoses in Humans and Animals

János Varga 1,* email, Sándor Kocsubé 1 email, Zsanett Péteri 1,2 email, Csaba Vágvölgyi 1 email and Beáta Tóth 3 email
1 Department of Microbiology, Faculty of Science and Informatics, University of Szeged, Közép fasor 52, H-6726 Szeged, Hungary 2 PannonPharma Company, Mária dűlő 36, H-7634 Pécs, Hungary 3 Cereal Research Non-Profit Limited Company, Alsókikötő sor 9, H-6726 Szeged, Hungary
* Author to whom correspondence should be addressed.
Received: 6 May 2010; in revised form: 25 June 2010 / Accepted: 29 June 2010 / Published: 1 July 2010
(This article belongs to the Special Issue Ochratoxins)
PDF Full-text Download PDF Full-Text [418 KB, uploaded 1 July 2010 13:42 CEST]
Abstract: Ochratoxins are polyketide derived fungal secondary metabolites with nephrotoxic, immunosuppressive, teratogenic, and carcinogenic properties. Ochratoxin-producing fungi may contaminate agricultural products in the field (preharvest spoilage), during storage (postharvest spoilage), or during processing. Ochratoxin contamination of foods and feeds poses a serious health hazard to animals and humans. Several strategies have been investigated for lowering the ochratoxin content in agricultural products. These strategies can be classified into three main categories: prevention of ochratoxin contamination, decontamination or detoxification of foods contaminated with ochratoxins, and inhibition of the absorption of consumed ochratoxins in the gastrointestinal tract. This paper gives an overview of the strategies that are promising with regard to lowering the ochratoxin burden of animals and humans.
Keywords: ochratoxin; detoxification; adsorption; spoilage

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Varga, J.; Kocsubé, S.; Péteri, Z.; Vágvölgyi, C.; Tóth, B. Chemical, Physical and Biological Approaches to Prevent Ochratoxin Induced Toxicoses in Humans and Animals. Toxins 2010, 2, 1718-1750.

AMA Style

Varga J, Kocsubé S, Péteri Z, Vágvölgyi C, Tóth B. Chemical, Physical and Biological Approaches to Prevent Ochratoxin Induced Toxicoses in Humans and Animals. Toxins. 2010; 2(7):1718-1750.

Chicago/Turabian Style

Varga, János; Kocsubé, Sándor; Péteri, Zsanett; Vágvölgyi, Csaba; Tóth, Beáta. 2010. "Chemical, Physical and Biological Approaches to Prevent Ochratoxin Induced Toxicoses in Humans and Animals." Toxins 2, no. 7: 1718-1750.

Toxins EISSN 2072-6651 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert