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Chemical, Physical and Biological Approaches to Prevent Ochratoxin Induced Toxicoses in Humans and Animals
Department of Microbiology, Faculty of Science and Informatics, University of Szeged, Közép fasor 52, H-6726 Szeged, Hungary
PannonPharma Company, Mária dűlő 36, H-7634 Pécs, Hungary
Cereal Research Non-Profit Limited Company, Alsókikötő sor 9, H-6726 Szeged, Hungary
* Author to whom correspondence should be addressed.
Received: 6 May 2010; in revised form: 25 June 2010 / Accepted: 29 June 2010 / Published: 1 July 2010
(This article belongs to the Special Issue Ochratoxins
Abstract: Ochratoxins are polyketide derived fungal secondary metabolites with nephrotoxic, immunosuppressive, teratogenic, and carcinogenic properties. Ochratoxin-producing fungi may contaminate agricultural products in the field (preharvest spoilage), during storage (postharvest spoilage), or during processing. Ochratoxin contamination of foods and feeds poses a serious health hazard to animals and humans. Several strategies have been investigated for lowering the ochratoxin content in agricultural products. These strategies can be classified into three main categories: prevention of ochratoxin contamination, decontamination or detoxification of foods contaminated with ochratoxins, and inhibition of the absorption of consumed ochratoxins in the gastrointestinal tract. This paper gives an overview of the strategies that are promising with regard to lowering the ochratoxin burden of animals and humans.
Keywords: ochratoxin; detoxification; adsorption; spoilage
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Varga, J.; Kocsubé, S.; Péteri, Z.; Vágvölgyi, C.; Tóth, B. Chemical, Physical and Biological Approaches to Prevent Ochratoxin Induced Toxicoses in Humans and Animals. Toxins 2010, 2, 1718-1750.
Varga J, Kocsubé S, Péteri Z, Vágvölgyi C, Tóth B. Chemical, Physical and Biological Approaches to Prevent Ochratoxin Induced Toxicoses in Humans and Animals. Toxins. 2010; 2(7):1718-1750.
Varga, János; Kocsubé, Sándor; Péteri, Zsanett; Vágvölgyi, Csaba; Tóth, Beáta. 2010. "Chemical, Physical and Biological Approaches to Prevent Ochratoxin Induced Toxicoses in Humans and Animals." Toxins 2, no. 7: 1718-1750.