Next Article in Journal
Life Events and the Onset of Celiac Disease from a Patient’s Perspective
Next Article in Special Issue
Polyphenols: Benefits to the Cardiovascular System in Health and in Aging
Previous Article in Journal
Association between Subcutaneous White Adipose Tissue and Serum 25-Hydroxyvitamin D in Overweight and Obese Adults
Previous Article in Special Issue
Biological Activities and Bioavailability of Mangosteen Xanthones: A Critical Review of the Current Evidence
Article Menu

Export Article

Open AccessReview
Nutrients 2013, 5(9), 3367-3387; doi:10.3390/nu5093367

Flavonoid Bioavailability and Attempts for Bioavailability Enhancement

Department of Environmental Sciences, Faculty of Agriculture, Dalhousie University, P.O. Box 550, Truro, NS B2N 5E3, Canada
*
Author to whom correspondence should be addressed.
Received: 10 June 2013 / Revised: 21 August 2013 / Accepted: 21 August 2013 / Published: 28 August 2013
(This article belongs to the Special Issue Polyphenols and Human Health)
View Full-Text   |   Download PDF [301 KB, uploaded 28 August 2013]   |  

Abstract

Flavonoids are a group of phytochemicals that have shown numerous health effects and have therefore been studied extensively. Of the six common food flavonoid classes, flavonols are distributed ubiquitously among different plant foods whereas appreciable amounts of isoflavones are found in leguminous plant-based foods. Flavonoids have shown promising health promoting effects in human cell culture, experimental animal and human clinical studies. They have shown antioxidant, hypocholesterolemic, anti-inflammatory effects as well as ability to modulate cell signaling and gene expression related disease development. Low bioavailability of flavonoids has been a concern as it can limit or even hinder their health effects. Therefore, attempts to improve their bioavailability in order to improve the efficacy of flavonoids are being studied. Further investigations on bioavailability are warranted as it is a determining factor for flavonoid biological activity. View Full-Text
Keywords: flavonoids; bioavailability; diet; health; disease flavonoids; bioavailability; diet; health; disease
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Thilakarathna, S.H.; Rupasinghe, H.P.V. Flavonoid Bioavailability and Attempts for Bioavailability Enhancement. Nutrients 2013, 5, 3367-3387.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top