Viruses 2010, 2(5), 1195-1217; doi:10.3390/v2051195

Lipid Metabolism and HCV Infection

1email, 2email, 3email and 4,* email
Received: 22 March 2010; in revised form: 5 May 2010 / Accepted: 6 May 2010 / Published: 11 May 2010
(This article belongs to the Special Issue Role of Lipids in Virus Replication)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Chronic infection by hepatitis C virus (HCV) can lead to severe liver disease and is a global healthcare problem. The liver is highly metabolically active and one of its key functions is to control the balance of lipid throughout the body. A number of pathologies have been linked to the impact of HCV infection on liver metabolism. However, there is also growing evidence that hepatic metabolic processes contribute to the HCV life cycle. This review summarizes the relationship between lipid metabolism and key stages in the production of infectious HCV.
Keywords: hepatitis C virus; HCV; lipid metabolism; lipid droplets; fatty acid biosynthesis; cholesterol biosynthesis; VLDL assembly; RNA replication; virus assembly
PDF Full-text Download PDF Full-Text [254 KB, uploaded 11 May 2010 16:45 CEST]

Export to BibTeX |

MDPI and ACS Style

Targett-Adams, P.; Boulant, S.; Douglas, M.W.; McLauchlan, J. Lipid Metabolism and HCV Infection. Viruses 2010, 2, 1195-1217.

AMA Style

Targett-Adams P, Boulant S, Douglas MW, McLauchlan J. Lipid Metabolism and HCV Infection. Viruses. 2010; 2(5):1195-1217.

Chicago/Turabian Style

Targett-Adams, Paul; Boulant, Steeve; Douglas, Mark W.; McLauchlan, John. 2010. "Lipid Metabolism and HCV Infection." Viruses 2, no. 5: 1195-1217.

Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert