Lipid Membranes in Poxvirus Replication
AbstractPoxviruses replicate in the cytoplasm, where they acquire multiple lipoprotein membranes. Although a proposal that the initial membrane arises de novo has not been substantiated, there is no accepted explanation for its formation from cellular membranes. A subsequent membrane-wrapping step involving modified trans-Golgi or endosomal cisternae results in a particle with three membranes. These wrapped virions traverse the cytoplasm on microtubules; the outermost membrane is lost during exocytosis, the middle one is lost just prior to cell entry, and the remaining membrane fuses with the cell to allow the virus core to enter the cytoplasm and initiate a new infection.
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Laliberte, J.P.; Moss, B. Lipid Membranes in Poxvirus Replication. Viruses 2010, 2, 972-986.
Laliberte JP, Moss B. Lipid Membranes in Poxvirus Replication. Viruses. 2010; 2(4):972-986.Chicago/Turabian Style
Laliberte, Jason P.; Moss, Bernard. 2010. "Lipid Membranes in Poxvirus Replication." Viruses 2, no. 4: 972-986.