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Bunyaviruses and the Type I Interferon System
Centre for Biomolecular Sciences, School of Biology, University of St. Andrews, St. Andrews, KY16 9ST, Scotland, UK
Department of Virology, University of Freiburg, D-79008 Freiburg, Germany
* Author to whom correspondence should be addressed.
Received: 21 September 2009; in revised form: 11 November 2009 / Accepted: 20 November 2009 / Published: 23 November 2009
Abstract: The family Bunyaviridae contains more than 350 viruses that are distributed throughout the world. Most members of the family are transmitted by arthopods, and several cause disease in man, domesticated animals and crop plants. Despite being recognized as an emerging threat, details of the virulence mechanisms employed by bunyaviruses are scant. In this article we summarise the information currently available on how these viruses are able to establish infection when confronted with a powerful antiviral interferon system.
Keywords: bunyaviruses; interferon system; NSs proteins
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Elliott, R.M.; Weber, F. Bunyaviruses and the Type I Interferon System. Viruses 2009, 1, 1003-1021.
Elliott RM, Weber F. Bunyaviruses and the Type I Interferon System. Viruses. 2009; 1(3):1003-1021.
Elliott, Richard M.; Weber, Friedemann. 2009. "Bunyaviruses and the Type I Interferon System." Viruses 1, no. 3: 1003-1021.