Next Article in Journal / Special Issue
Real or Illusory? Case Studies on the Public Perception of Environmental Health Risks in the North West of England
Previous Article in Journal
Food Patterns According to Sociodemographics, Physical Activity, Sleeping and Obesity in Portuguese Children
Previous Article in Special Issue
Human Amebiasis: Breaking the Paradigm?
Int. J. Environ. Res. Public Health 2010, 7(3), 1139-1152; doi:10.3390/ijerph7031139
Communication

A Multidisciplinary Investigation of a Polycythemia Vera Cancer Cluster of Unknown Origin

1,* , 1
, 1
, 1
, 1
, 1
, 1
, 1
, 2
, 2
, 2
, 3
, 3
, 4
, 4
, 4
, 4
, 5
, 5
, 5
, 6
, 6
, 6
, 7
, 7
, 7
, 7, 8
, 9
 and 10
1 Agency for Toxic Substances and Disease Registry, 4770 Buford Highway NE, Atlanta, GA, 30341, USA 2 Pennsylvania Department of Health, 7th & Forster Streets, Harrisburg, PA 17120, USA 3 Mt. Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029-6574, USA 4 Geisinger Health System/Clinic, 100 N. Academy Ave, Danville, PA 17822, USA 5 Pennsylvania Department of Environmental Protection, 2 Public Square, Wilkes-Barre, PA 18711, USA 6 Centers for Disease Control and Prevention, National Program of Cancer Registries, 1600 Clifton, Rd NE, Atlanta, GA 30333, USA 7 Drexel University School of Public Health, 1505 Race Street, Bellet Building 13th Floor, Philadelphia, PA, 19102, USA 8 UPMC Cancer Pavilion, 3rd Floor, 5150 Centre Avenue, Pittsburgh, PA 15232, USA 9 New York Blood Center, 310 East 67th Street, 2-47B, New York, NY 10065, USA 10 Henry S. Cole & Associates, 7611 S. Osborne Rd, Ste 201, Upper Marlboro, MD 20772, USA
* Author to whom correspondence should be addressed.
Received: 29 January 2010 / Revised: 13 March 2010 / Accepted: 16 March 2010 / Published: 17 March 2010
(This article belongs to the Special Issue Advances in Epidemiology)
View Full-Text   |   Download PDF [67 KB, 19 June 2014; original version 19 June 2014]

Abstract

Cancer cluster investigations rarely receive significant public health resource allocations due to numerous inherent challenges and the limited success of past efforts. In 2008, a cluster of polycythemia vera, a rare blood cancer with unknown etiology, was identified in northeast Pennsylvania. A multidisciplinary group of federal and state agencies, academic institutions, and local healthcare providers subsequently developed a multifaceted research portfolio designed to better understand the cause of the cluster. This research agenda represents a unique and important opportunity to demonstrate that cancer cluster investigations can produce desirable public health and scientific outcomes when necessary resources are available.
Keywords: polycythemia vera; cancer cluster; environmental exposure; Pennsylvania polycythemia vera; cancer cluster; environmental exposure; Pennsylvania
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Export to BibTeX |
EndNote


MDPI and ACS Style

Seaman, V.; Dearwent, S.M.; Gable, D.; Lewis, B.; Metcalf, S.; Orloff, K.; Tierney, B.; Zhu, J.; Logue, J.; Marchetto, D.; Ostroff, S.; Hoffman, R.; Xu, M.; Carey, D.; Erlich, P.; Gerhard, G.; Roda, P.; Iannuzzo, J.; Lewis, R.; Mellow, J.; Mulvihill, L.; Myles, Z.; Wu, M.; Frank, A.; Gross-Davis, C.A.; Klotz, J.; Lynch, A.; Weissfeld, J.; Weinberg, R.; Cole, H. A Multidisciplinary Investigation of a Polycythemia Vera Cancer Cluster of Unknown Origin. Int. J. Environ. Res. Public Health 2010, 7, 1139-1152.

View more citation formats

Related Articles

Article Metrics

Comments

Citing Articles

[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert