Next Article in Journal
Seasonal Differences in the Day-of-the-Week Pattern of Suicide in Queensland, Australia
Next Article in Special Issue
Workplace Bullying among Healthcare Workers
Previous Article in Journal
A Bayesian Approach to Estimate the Prevalence of Schistosomiasis japonica Infection in the Hubei Province Lake Regions, China
Previous Article in Special Issue
Generational Differences in Work-Family Conflict and Synergy
Article Menu

Export Article

Open AccessArticle
Int. J. Environ. Res. Public Health 2013, 10(7), 2813-2824; doi:10.3390/ijerph10072813

Circulating Nitrite and Nitrate are Associated with Job-Related Fatigue in Women, but not in Men

Department of Public Health and Occupational Medicine, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
Received: 29 May 2013 / Revised: 23 June 2013 / Accepted: 26 June 2013 / Published: 5 July 2013
(This article belongs to the Special Issue Job Stress and Health)
View Full-Text   |   Download PDF [225 KB, uploaded 19 June 2014]   |  

Abstract

A recent study indicated that serum nitrite and nitrate (NOx) is inversely associated with general fatigue. The purpose of this study was to confirm the negative association between nitric oxide (NO) and fatigue and to examine whether NO can prevent fatigue caused by job strain. The subjects, 570 workers (272 men and 298 women), answered self-administered questionnaires and underwent a medical examination. Job strain was measured using the Job Content Questionnaire. Fatigue was evaluated using the Profile of Mood States. Venous blood samples were collected after overnight fasting. Plasma NOx concentration was determined by the ozone-based chemiluminescence assay. Plasma NOx levels were significantly (p < 0.05) negatively associated with fatigue even after adjustment for job strain and potential confounders in women, but not in men. Significant (p < 0.05) interactions showed that, in women, as the level of the job strain worsened, fatigue was exacerbated, but the plasma NOx seemed to buffer the association, even after adjustment for potential confounders and the interaction between job strain and vegetable intake. In women, NO seemed to be inversely associated with fatigue and to buffer the association between job strain and fatigue, but not in men.
Keywords: interaction; demands-control model; fatigue; gender difference; job strain; nitric oxide interaction; demands-control model; fatigue; gender difference; job strain; nitric oxide
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Takaki, J. Circulating Nitrite and Nitrate are Associated with Job-Related Fatigue in Women, but not in Men. Int. J. Environ. Res. Public Health 2013, 10, 2813-2824.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top