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Pharmaceuticals 2010, 3(5), 1561-1575; doi:10.3390/ph3051561

Review

Chemoprophylaxis of Tropical Infectious Diseases

William J. H. McBride

School of Medicine and Dentistry, James Cook University, Cairns Base Hospital campus, The Esplanade, Cairns, Queensland 4870, Australia

Received: 8 April 2010; in revised form: 28 April 2010 / Accepted: 10 May 2010 / Published: 18 May 2010

(This article belongs to the Special Issue Tropical Medicine)

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Abstract: Travelers to tropical countries are at risk for a variety of infectious diseases. In some cases effective vaccinations are available, but for other infections chemoprophylaxis can be offered. Malaria prevention has become increasingly complex as Plasmodium species become resistant to available drugs. In certain high risk settings, antibiotics can be used to prevent leptospirosis, scrub typhus and other infections. Post-exposure prophylaxis is appropriate for selected virulent infections. In this article the evidence for chemoprophylaxis will be reviewed.

Keywords: chemoprophylaxis; malaria; leptospirosis; scrub typhus; diarrhea

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