Next Article in Journal
Neurotrauma: The Crosstalk between Neurotrophins and Inflammation in the Acutely Injured Brain
Next Article in Special Issue
Examining the Overlap between Autism Spectrum Disorder and 22q11.2 Deletion Syndrome
Previous Article in Journal
Biofilm is a Major Virulence Determinant in Bacterial Colonization of Chronic Skin Ulcers Independently from the Multidrug Resistant Phenotype
Previous Article in Special Issue
Clock Genes and Altered Sleep–Wake Rhythms: Their Role in the Development of Psychiatric Disorders
Article Menu
Issue 5 (May) cover image

Export Article

Open AccessArticle
Int. J. Mol. Sci. 2017, 18(5), 1078; doi:10.3390/ijms18051078

Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample

1
NORMENT, KG Jebsen Centre for Psychosis Research, University of Oslo, Oslo 0424, Norway
2
Division of Mental Health and Addiction, Oslo University Hospital, Oslo 0315, Norway
3
Department of Medical Genetics, Oslo University Hospital, Oslo 0424, Norway
4
NevSom, Department of Rare Disorders and Disabilities, Oslo University Hospital, Oslo 0424, Norway
5
Autism Society Norway, Oslo 0609, Norway
6
Department of Neurohabilitation, Oslo University Hospital, Oslo 0424, Norway
7
Regional Centre for Child and Youth Mental Health and Child Welfare, Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim 7491, Norway
8
Department of Pediatrics, St. Olavs Hospital, Trondheim University Hospital, Trondheim 7006, Norway
9
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim 68159, Germany
10
Division of Mental Health and Addiction, Vestre Viken Hospital Trust, Drammen 3004, Norway
11
Department of Clinical Science, University of Bergen, Bergen 5021, Norway
The authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Merlin G. Butler
Received: 27 February 2017 / Revised: 12 May 2017 / Accepted: 13 May 2017 / Published: 18 May 2017
View Full-Text   |   Download PDF [246 KB, uploaded 18 May 2017]

Abstract

Clinical genetic testing (CGT) of children with autism spectrum disorder (ASD) may have positive and negative effects. Knowledge about parents’ attitudes is needed to ensure good involvement of caregivers, which is crucial for accurate diagnosis and effective clinical management. This study aimed to assess parents’ attitudes toward CGT for ASD. Parent members of the Norwegian Autism Society were given a previously untested questionnaire and 1455 answered. Linear regression analyses were conducted to evaluate contribution of parent and child characteristics to attitude statements. Provided it could contribute to a casual explanation of their child’s ASD, 76% would undergo CGT. If it would improve the possibilities for early interventions, 74% were positive to CGT. Between 49–67% agreed that CGT could have a negative impact on health insurance, increase their concern for the child’s future and cause family conflicts. Parents against CGT (9%) were less optimistic regarding positive effects, but not more concerned with negative impacts. The severity of the children’s ASD diagnosis had a weak positive association with parent’s positive attitudes to CGT (p-values range from <0.001 to 0.975). Parents prefer that CGT is offered to those having a child with ASD (65%), when the child’s development deviates from normal (48%), or before pregnancy (36%). A majority of the parents of children with ASD are positive to CGT due to possibilities for an etiological explanation. View Full-Text
Keywords: ASD; autism; Asperger syndrome; clinical genetic testing; parents; attitudes; ethics; genetic counselling ASD; autism; Asperger syndrome; clinical genetic testing; parents; attitudes; ethics; genetic counselling
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Johannessen, J.; Nærland, T.; Hope, S.; Torske, T.; Høyland, A.L.; Strohmaier, J.; Heiberg, A.; Rietschel, M.; Djurovic, S.; Andreassen, O.A. Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample. Int. J. Mol. Sci. 2017, 18, 1078.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top