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Int. J. Mol. Sci. 2013, 14(8), 17168-17192; doi:10.3390/ijms140817168

Preventive or Potential Therapeutic Value of Nutraceuticals against Ionizing Radiation-Induced Oxidative Stress in Exposed Subjects and Frequent Fliers

1
IC-CNR Area della ricerca di Roma, Monterotondo scalo 00015, Italy
2
Biosensor, Via Olmetti 44 Formello, Rome 00060, Italy
3
Department of Chemistry, University of Crete, P.O. Box 2208, Voutes-Heraklion 71003, Greece
4
Agenzia Spaziale Italiana (ASI), Viale Liegi 26, Rome 00198, Italy
*
Author to whom correspondence should be addressed.
Received: 15 March 2013 / Revised: 1 August 2013 / Accepted: 12 August 2013 / Published: 20 August 2013
(This article belongs to the Special Issue Oxidative Stress and Ageing)
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Abstract

Humans are constantly exposed to ionizing radiation deriving from outer space sources or activities related to medical care. Absorption of ionizing radiation doses over a prolonged period of time can result in oxidative damage and cellular dysfunction inducing several diseases, especially in ageing subjects. In this report, we analyze the effects of ionizing radiation, particularly at low doses, in relation to a variety of human pathologies, including cancer, and cardiovascular and retinal diseases. We discuss scientific data in support of protection strategies by safe antioxidant formulations that can provide preventive or potential therapeutic value in response to long-term diseases that may develop following exposure.
Keywords: ionizing radiation; low doses; oxidation stress; ageing; cardiovascular disease; cancer; retina degeneration; antioxidants; radio-protection ionizing radiation; low doses; oxidation stress; ageing; cardiovascular disease; cancer; retina degeneration; antioxidants; radio-protection
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Giardi, M.T.; Touloupakis, E.; Bertolotto, D.; Mascetti, G. Preventive or Potential Therapeutic Value of Nutraceuticals against Ionizing Radiation-Induced Oxidative Stress in Exposed Subjects and Frequent Fliers. Int. J. Mol. Sci. 2013, 14, 17168-17192.

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