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Role of Melatonin in Schizophrenia
Department of Internal Medicine, Dermatology and Psychiatry, School of Medicine, University of La Laguna, 38071 La Laguna, Spain
Psychiatric Consultancy SC, 38001 Santa Cruz de Tenerife, Spain
Department of Physiology, School of Medicine, University of La Laguna, 38071 La Laguna, Spain
* Author to whom correspondence should be addressed.
Received: 19 February 2013; in revised form: 9 April 2013 / Accepted: 10 April 2013 / Published: 25 April 2013
Abstract: Schizophrenia is a chronic mental disease that disturbs several cognitive functions, such as memory, thought, perception and volition. Schizophrenia’s biological etiology is multifactorial and is still under investigation. Melatonin has been involved in schizophrenia since the first decades of the twentieth century. Research into melatonin regarding schizophrenia has followed two different approaches. The first approach is related to the use of melatonin as a biological marker. The second approach deals with the clinical applications of melatonin as a drug treatment. In this paper, both aspects of melatonin application are reviewed. Its clinical use in schizophrenia is emphasized.
Keywords: melatonin; schizophrenia; biological marker; therapeutic agent
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MDPI and ACS Style
Morera-Fumero, A.L.; Abreu-Gonzalez, P. Role of Melatonin in Schizophrenia. Int. J. Mol. Sci. 2013, 14, 9037-9050.
Morera-Fumero AL, Abreu-Gonzalez P. Role of Melatonin in Schizophrenia. International Journal of Molecular Sciences. 2013; 14(5):9037-9050.
Morera-Fumero, Armando L.; Abreu-Gonzalez, Pedro. 2013. "Role of Melatonin in Schizophrenia." Int. J. Mol. Sci. 14, no. 5: 9037-9050.