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Int. J. Mol. Sci. 2013, 14(5), 9037-9050; doi:10.3390/ijms14059037

Role of Melatonin in Schizophrenia

1,2,*  and 3
1 Department of Internal Medicine, Dermatology and Psychiatry, School of Medicine, University of La Laguna, 38071 La Laguna, Spain 2 Psychiatric Consultancy SC, 38001 Santa Cruz de Tenerife, Spain 3 Department of Physiology, School of Medicine, University of La Laguna, 38071 La Laguna, Spain
* Author to whom correspondence should be addressed.
Received: 19 February 2013 / Revised: 9 April 2013 / Accepted: 10 April 2013 / Published: 25 April 2013
(This article belongs to the Special Issue Advances in the Research of Melatonin)
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Schizophrenia is a chronic mental disease that disturbs several cognitive functions, such as memory, thought, perception and volition. Schizophrenia’s biological etiology is multifactorial and is still under investigation. Melatonin has been involved in schizophrenia since the first decades of the twentieth century. Research into melatonin regarding schizophrenia has followed two different approaches. The first approach is related to the use of melatonin as a biological marker. The second approach deals with the clinical applications of melatonin as a drug treatment. In this paper, both aspects of melatonin application are reviewed. Its clinical use in schizophrenia is emphasized.
Keywords: melatonin; schizophrenia; biological marker; therapeutic agent melatonin; schizophrenia; biological marker; therapeutic agent
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Morera-Fumero, A.L.; Abreu-Gonzalez, P. Role of Melatonin in Schizophrenia. Int. J. Mol. Sci. 2013, 14, 9037-9050.

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