Next Article in Journal
Weed Suppressing Potential and Isolation of Potent Plant Growth Inhibitors from Castanea crenata Sieb. et Zucc
Next Article in Special Issue
Applications of Cancer Cell-Specific Aptamers in Targeted Delivery of Anticancer Therapeutic Agents
Previous Article in Journal
Efficacy of Compounds Isolated from the Essential Oil of Artemisia lavandulaefolia in Control of the Cigarette Beetle, Lasioderma serricorne
Previous Article in Special Issue
A Lateral Flow Strip Based Aptasensor for Detection of Ochratoxin A in Corn Samples
Article Menu
Issue 2 (February) cover image

Export Article

Open AccessReview
Molecules 2018, 23(2), 344; https://doi.org/10.3390/molecules23020344

Practical Application of Aptamer-Based Biosensors in Detection of Low Molecular Weight Pollutants in Water Sources

School of Medicine, Huaqiao University, Quanzhou 362021, Fujian, China
*
Author to whom correspondence should be addressed.
Received: 9 January 2018 / Revised: 30 January 2018 / Accepted: 30 January 2018 / Published: 7 February 2018
(This article belongs to the Special Issue Nucleic Acid Aptamers)
Full-Text   |   PDF [504 KB, uploaded 7 February 2018]   |  

Abstract

Water pollution has become one of the leading causes of human health problems. Low molecular weight pollutants, even at trace concentrations in water sources, have aroused global attention due to their toxicity after long-time exposure. There is an increased demand for appropriate methods to detect these pollutants in aquatic systems. Aptamers, single-stranded DNA or RNA, have high affinity and specificity to each of their target molecule, similar to antigen-antibody interaction. Aptamers can be selected using a method called Systematic Evolution of Ligands by EXponential enrichment (SELEX). Recent years we have witnessed great progress in developing aptamer selection and aptamer-based sensors for low molecular weight pollutants in water sources, such as tap water, seawater, lake water, river water, as well as wastewater and its effluents. This review provides an overview of aptamer-based methods as a novel approach for detecting low molecular weight pollutants in water sources. View Full-Text
Keywords: aptamer; low molecular weight pollutant; water source; biosensor; environmental monitoring aptamer; low molecular weight pollutant; water source; biosensor; environmental monitoring
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Zhang, W.; Liu, Q.X.; Guo, Z.H.; Lin, J.S. Practical Application of Aptamer-Based Biosensors in Detection of Low Molecular Weight Pollutants in Water Sources. Molecules 2018, 23, 344.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top