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Molecules 2017, 22(3), 471; doi:10.3390/molecules22030471

A Metabolomic Approach for the Discrimination of Red Ginseng Root Parts and Targeted Validation

Korea Ginseng Research Institute, Korea Ginseng Corporation, Daejeon 305-805, Korea
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Author to whom correspondence should be addressed.
Academic Editors: Woo-Sik Jeong, Anusha Chaparala and Lorne Hofseth
Received: 15 February 2017 / Revised: 13 March 2017 / Accepted: 13 March 2017 / Published: 15 March 2017
(This article belongs to the Special Issue Current Trends in Ginseng Research)
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Abstract

Ginsenosides are used as existing markers of red ginseng (RG) quality, and ginsenoside ratios are also indicative of the different components of red ginseng. For the analysis and classification of ginsenoside content, red ginseng was separated into three parts, namely, main roots, lateral roots, and fine roots, and each extract was subjected to ultra-performance liquid chromatography quadruple time-of-flight mass spectrometry (UPLC-QToF-MS) with multivariate statistical analysis. Principal component analysis (PCA) showed a clear discrimination between the extracts of main roots and fine roots and suggested discrimination markers (four for the main roots and five for the fine roots). The fine root markers were identified as ginsenoside. We identified two markers for the main roots of red ginseng in this study. Moreover, the contents of 22 ginsenosides were analyzed in all three components of red ginseng. Fine roots have the highest protopanaxadiol (PPD)/protopanaxatriol (PPT) ratio. The PPD group of ginsenosides, which is quantitatively dominant in fine roots, clearly distinguishes the main roots from the other parts. View Full-Text
Keywords: Panax ginseng; red ginseng (RG); metabolomics; ultra-performance liquid chromatography quadruple time-of-flight mass spectrometry (UPLC-QToF-MS) Panax ginseng; red ginseng (RG); metabolomics; ultra-performance liquid chromatography quadruple time-of-flight mass spectrometry (UPLC-QToF-MS)
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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In, G.; Seo, H.K.; Park, H.-W.; Jang, K.H. A Metabolomic Approach for the Discrimination of Red Ginseng Root Parts and Targeted Validation. Molecules 2017, 22, 471.

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