Next Article in Journal
Small versus Large Iron Oxide Magnetic Nanoparticles: Hyperthermia and Cell Uptake Properties
Next Article in Special Issue
Deep Eutectic Solvent-Based Microwave-Assisted Method for Extraction of Hydrophilic and Hydrophobic Components from Radix Salviae miltiorrhizae
Previous Article in Journal
Three New Butenolides from the Fungus Aspergillus sp. CBS-P-2
Previous Article in Special Issue
Enzymatic Synthesis of Glucose-Based Fatty Acid Esters in Bisolvent Systems Containing Ionic Liquids or Deep Eutectic Solvents
Article Menu
Issue 10 (October) cover image

Export Article

Open AccessCommunication
Molecules 2016, 21(10), 1355; doi:10.3390/molecules21101355

Exploiting 1,2,3-Triazolium Ionic Liquids for Synthesis of Tryptanthrin and Chemoselective Extraction of Copper(II) Ions and Histidine-Containing Peptides

Department of Chemistry and Biochemistry, National Chung Cheng University, Chiayi 62102, Taiwan
Both authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Hua Zhao
Received: 29 August 2016 / Revised: 5 October 2016 / Accepted: 9 October 2016 / Published: 13 October 2016
View Full-Text   |   Download PDF [2584 KB, uploaded 13 October 2016]   |  

Abstract

Based on a common structural core of 4,5,6,7-tetrahydro[1,2,3]triazolo[1,5-a]pyridine, a number of bicyclic triazolium ionic liquids 13 were designed and successfully prepared. In our hands, this optimized synthesis of ionic liquids 1 and 2 requires no chromatographic separation. Also in this work, ionic liquids 1, 2 were shown to be efficient ionic solvents for fast synthesis of tryptanthrin natural product. Furthermore, a new affinity ionic liquid 3 was tailor-synthesized and displayed its effectiveness in chemoselective extraction of both Cu(II) ions and, for the first time, histidine-containing peptides. View Full-Text
Keywords: ionic liquid; Cu-free click reaction; tryptanthrin synthesis; affinity ionic liquid; copper ion; chemoselective extraction; peptide ionic liquid; Cu-free click reaction; tryptanthrin synthesis; affinity ionic liquid; copper ion; chemoselective extraction; peptide
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Li, H.-Y.; Chen, C.-Y.; Cheng, H.-T.; Chu, Y.-H. Exploiting 1,2,3-Triazolium Ionic Liquids for Synthesis of Tryptanthrin and Chemoselective Extraction of Copper(II) Ions and Histidine-Containing Peptides. Molecules 2016, 21, 1355.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top